ReviewInternational journal of molecular sciences2022
Increasing Heavy Metal Tolerance by the Exogenous Application of Organic Acids.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Exogenous pipecolic acid ameliorates lead-induced phytotoxicity in chili (Plant signaling & behavior · 2026Article
- Foliar serotonin and allantoin mitigate tellurium toxicity in Quinoa (Plant signaling & behavior · 2026Article
- Organic acids counteract the determinate root development induced by phosphate deprivation inPlant signaling & behavior · 2026Article
- Evaluation of chickpea (Cicer arietinum L.) varieties under ZnSODie Naturwissenschaften · 2026Article
- Mechanistic insights into organic acid-mediated mitigation of nickel toxicity in maize (Zea mays L.) grown on mining-impacted soils.BMC plant biology · 2026Article
- Harnessing biostimulants to alleviate potentially toxic element stress in vegetable crops.Planta · 2026Review
- A review of toxicity and remediation: thorium uptake by woody plants.Biodegradation · 2026Review
- Hormonal Status and the Probable Role of Phytohormones in Response of Pea Cultivar Sparkle and Mutant E107 (Plants (Basel, Switzerland) · 2026Article
- Dopamine modulates antioxidant and phenolic responses to alleviate nickel stress in Salvia officinalis.BMC plant biology · 2026Article
- Article
- Restoring landscapes and communities: Insights from critical, urban, and plant ecology.Environmental science and ecotechnology · 2025Review
- Regulatory Mechanisms of Phenolic Acids in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Review.Antioxidants (Basel, Switzerland) · 2025Review
- The Significance of Rhizobacteria for Strawberry Cultivation in Tropical Area: A Review.Tropical life sciences research · 2025Article
- Efficacy of malic and tartaric acid in mitigation of cadmium stress in Spinacia oleracea L. via modulations in physiological and biochemical attributes.Scientific reports · 2025Article
- Pretreatment with aqueousHeliyon · 2024Article
- The Role of Low-Molecular-Weight Organic Acids in Metal Homeostasis in Plants.International journal of molecular sciences · 2024Review
- Salicylic acid and jasmonic acid-mediated different fate of nickel phytoremediation in two populations of Alyssum inflatum Nyár.Scientific reports · 2024Article
- Transcriptomics, proteomics, and metabolomics interventions prompt crop improvement against metal(loid) toxicity.Plant cell reports · 2024Review
- Zinc Oxide Nanoparticles Affect Early Seedlings' Growth and Polar Metabolite Profiles of Pea (International journal of molecular sciences · 2023Article
- Methylglyoxal improves zirconium stress tolerance in Raphanus sativus seedling shoots by restricting zirconium uptake, reducing oxidative damage, and upregulating glyoxalase I.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Several metals belong to a group of non-biodegradable inorganic constituents that, at low concentrations, play fundamental roles as essential micronutrients for the growth and development of plants. However, in high concentrations they can have toxic and/or mutagenic effects, which can be counteracted by natural chemical compounds called chelators. Chelators have a diversity of chemical structures; many are organic acids, including carboxylic acids and cyclic phenolic acids. The exogenous application of such compounds is a non-genetic approach, which is proving to be a successful strategy to reduce damage caused by heavy metal toxicity. In this review, we will present the latest literature on the exogenous addition of both carboxylic acids, including the Kreb's Cycle intermediates citric and malic acid, as well as oxalic acid, lipoic acid, and phenolic acids (gallic and caffeic acid). The use of two non-traditional organic acids, the phytohormones jasmonic and salicylic acids, is also discussed. We place particular emphasis on physiological and molecular responses, and their impact in increasing heavy metal tolerance, especially in crop species.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.