Evidence map›Paper›PMID 35628110›Full record

ArticleInternational journal of molecular sciences2022

Glucosylceramide Changes Bacterial Metabolism and Increases Gram-Positive Bacteria through Tolerance to Secondary Bile Acids In Vitro.

Huanghuang Dai, Akira Otsuka, Kurumi Tanabe, Teruyoshi Yanagita, Jiro Nakayama, Hiroshi Kitagaki

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Central Roles of Glucosylceramide in Driving Cancer Pathogenesis.International journal of molecular sciences · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Interactive Relationships between Intestinal Flora and Bile Acids.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Huanghuang DaiThe United Graduate School of Agricultural Sciences, Kagoshima University, Korimoto 1-21-24, Kagoshima 890-0065, Japan.
Akira OtsukaGraduate School of Health Sciences, Saga University, Honjo-cho, 1, Saga 840-8502, Japan.
Kurumi TanabeGraduate School of Health Sciences, Saga University, Honjo-cho, 1, Saga 840-8502, Japan.
Teruyoshi YanagitaFaculty of Agriculture, Saga University, Honjo-cho, 1, Saga 840-8502, Japan.
Jiro NakayamaDivision of Systems Bioengineering, Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University, Motooka 744, Nishi-ku, Fukuoka 819-0395, Japan.
Hiroshi KitagakiThe United Graduate School of Agricultural Sciences, Kagoshima University, Korimoto 1-21-24, Kagoshima 890-0065, Japan.ORCID 0000-0001-6853-1412
Kagoshima University · JPSaga University · JPKyushu University · JPNishikyushu University · JP

Funding

Japan Society for the Promotion of Science 20K05809
6 · The paper itself

Abstract

Glucosylceramide is present in many foods, such as crops and fermented foods. Most glucosylceramides are not degraded or absorbed in the small intestine and pass through the large intestine. Glucosylceramide exerts versatile effects on colon tumorigenesis, skin moisture, cholesterol metabolism and improvement of intestinal microbes in vivo. However, the mechanism of action has not yet been fully elucidated. To gain insight into the effect of glucosylceramide on intestinal microbes, glucosylceramide was anaerobically incubated with the dominant intestinal microbe,

Indexed as

Bile Acids and SaltsGlucosylceramidesBacteriaGram-Positive BacteriaIntestinesBile Acids and SaltsGlucosylceramidesbile acidsBlautia coccoidesglucosylceramideintestinal microbesprebiotics

Identifiers

PMID35628110
PMCPMC9141989
OpenAlexW4229442930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.