ArticleHealthcare (Basel, Switzerland)2022
Uterine Fibroids and Pregnancy: A Review of the Challenges from a Romanian Tertiary Level Institution.
Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 27 citations in OpenAlex.
- A comparative analysis of the impact of three distinct laparoscopic myomectomy techniques on ovarian reserve: a randomized clinical trial.Archives of gynecology and obstetrics · 2025Trial
- Maternal and neonatal outcomes following cesarean myomectomy: a comparison between fibroid-associated and fibroid-free cesarean deliveries.Journal of the Turkish German Gynecological Association · 2026Article
- Spontaneous Rupture of Uterine Vessels Complicated with Placental Abruption: A Rare Case Report.International journal of women's health · 2026Article
- Influence of uterine fibroid size on perinatal and neonatal outcomes: a single-centre cohort of 651 pregnancies.BMC pediatrics · 2025Article
- An Unusual and Successful Pregnancy With Multiple Large Uterine Fibroids Delivered by Cesarean Myomectomy.Journal of medical cases · 2025Article
- Pregnancy Complicated by Ruptured Degenerating Leiomyoma and Hemoperitoneum: Case Report.Clinical medicine insights. Case reports · 2025Article
- The characteristics of a fibroid in pregnancy can influence the perinatal outcome.Archives of gynecology and obstetrics · 2024Article
- Spontaneous regression of a giant uterine leiomyoma after delivery: a case report and literature review.BMC pregnancy and childbirth · 2024Review
- Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesUterine fibroids are relatively common in reproductive-age women and are directly linked to pregnancy. There are many debates about performing a myomectomy at the same time as a caesarian section (CS) in such cases due to the risk of a hemorrhage. Our study aims to investigate fibroid features and their evolution in pregnancy, complications of a myomectomy during CS and maternal and fetal obstetric outcomes of pregnancies with fibroids. MATERIALS AND
methodsWe realize a prospective study that includes 57 patients with fibroids in pregnancy diagnosed in January 2017-June 2019. We analyze the number, the location and the growth of fibroids during pregnancy and the maternal and fetal outcome. We appreciate the bleeding in patients with a myomectomy and without a myomectomy during CS, using hemoglobin values before and after birth.
resultsMost of the patients present single fibroids that are 30-160 mm in size, located on the anterior uterine wall. Vaginal delivery is used in 7% of women, whereas 85.96% deliver by CS. In addition, 68% of fibroids are diagnosed in the first trimester. In most cases, the fibroid has maximum growth in the second trimester of pregnancy. The myomectomy rate for fibroids during CS is 24.48. Hemoglobin values showed no statistically significant difference between the two groups with and without myomectomy. The operating time is double for the group with a myomectomy associated with a CS. The results of the obstetric outcomes are abortion in 7% of all patients, whereas premature delivery and births at term are 9.43% and 90.57%, respectively.
conclusionsThe decision of performing a myomectomy during pregnancy can be a challenge and must be performed for selected cases. This procedure may have several benefits, such as avoiding another operation to remove fibroids.
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