Evidence map›Paper›PMID 35627945›Full record

ArticleHealthcare (Basel, Switzerland)2022

Differential Methylation Analysis of Suicidal Ideation Severity in Schizophrenia with the Illumina MethylationEPIC Array.

Kevin Z Wang, Zanib Chaudhary, Jessica Qian, Christopher Adanty, Ariel Graff-Guerrero, Philip Gerretsen, Clement C Zai, Vincenzo De Luca

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Epigenome-wide Association Study for Tic Disorders in Children: A Preliminary Study in Korean Population.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kevin Z WangDepartment of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.
Zanib ChaudharyDepartment of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.
Jessica QianDepartment of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.
Christopher AdantyDepartment of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.
Ariel Graff-GuerreroDepartment of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.
Philip GerretsenDepartment of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.
Clement C ZaiDepartment of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.
Vincenzo De LucaDepartment of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.
University of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a multitude of factors that makes difficult to identify those at risk for suicide, especially among schizophrenia patients. Suicide cannot be explained by genetics alone, therefore epigenetic mechanisms including DNA methylation are thought to play a role. DNA methylation could be a valuable tool in helping predict those at-risk individuals. This cross-sectional study comprised 112 subjects diagnosed with schizophrenia spectrum disorders, and were grouped according to the current suicidal ideation severity. DNA methylation across the genome was measured with the Infinium

Indexed as

C-SSRSDNA methylationIllumina EPICschizophreniasuicide

Identifiers

PMID35627945
PMCPMC9141768
OpenAlexW4282914280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.