ArticleInternational journal of environmental research and public health2022
COVID-19 Myocarditis: Prognostic Role of Bedside Speckle-Tracking Echocardiography and Association with Total Scar Burden.
Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cardiac Magnetic Resonance Imaging of COVID-19-Associated Cardiac Sequelae: A Systematic Review.Reviews in cardiovascular medicine · 2022Pooled it
- Effectiveness and safety of Linggui Zhugan decoction for the treatment of premature contraction in patients with coronary heart disease: A systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Editorial: Advancing sports cardiology: new frontiers in athlete screening and recovery.Frontiers in cardiovascular medicine · 2026Article
- Correlation of acute myocardial injury and long-term cardiac function in COVID-19 survivors with acute myocarditis.Archives of medical sciences. Atherosclerotic diseases · 2025Article
- Exercise Stress Echocardiography in Athletes: Applications, Methodology, and Challenges.Journal of clinical medicine · 2023Review
- Echocardiographic Assessment in Patients Recovered from Acute COVID-19 Illness.Journal of cardiovascular development and disease · 2023Article
- Effects on Right Ventricular Function One Year after COVID-19-Related Pulmonary Embolism.Journal of clinical medicine · 2023Article
- Strain Echocardiography in Acute COVID-19 and Post-COVID Syndrome: More than Just a Snapshot.Biomedicines · 2023Review
- Are Football Players More Prone to Muscle Injury after COVID-19 Infection? The "Italian Injury Study" during the Serie a Championship.International journal of environmental research and public health · 2023Article
- COVID-19 and Cardiovascular Diseases: A Literature Review From Pathogenesis to Diagnosis.Cureus · 2023Review
- Ultrasound during the COVID-19 Pandemic: A Global Approach.Journal of clinical medicine · 2023Review
- Mitochondria Dysfunction at the Heart of Viral Myocarditis: Mechanistic Insights and Therapeutic Implications.Viruses · 2023Review
- Persistent Chest Pain after COVID-19 Infection. Can Strain Echo Parameters Play a Role in Diagnosis and Prognostication?Arquivos brasileiros de cardiologia · 2023Article
- Impaired Speckle-Tracking-Derived Left Ventricular Longitudinal Strain Is Associated with Transposition of Great Arteries in Neonates: A Single-Center Study.International journal of environmental research and public health · 2022Article
- Tendentious Paper-Titles and Wrong Conclusions Lead to Fear in the Population and Medical Overconsumption. Comment on Luchian et al. Subclinical Myocardial Dysfunction in Patients with Persistent Dyspnea One Year after COVID-19.Diagnostics (Basel, Switzerland) · 2022Article
- Article
- Two-dimensional Speckle-Tracking and Four-dimensional Echocardiographic Evaluation of Cardiac Involvement in Post-COVID-19 patients: Comparison of Symptomatic and Asymptomatic Groups.Journal of cardiovascular echographyArticle
- A stroke in severe acute respiratory syndrome coronavirus 2 infected is not necessarily a COVID-stroke.Brain circulationArticle
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
SARS-CoV2 infection, responsible for the COVID-19 disease, can determine cardiac as well as respiratory injury. In COVID patients, viral myocarditis can represent an important cause of myocardial damage. Clinical presentation of myocarditis is heterogeneous. Furthermore, the full diagnostic algorithm can be hindered by logistical difficulties related to the transportation of COVID-19 patients in a critical condition to the radiology department. Our aim was to study longitudinal systolic cardiac function in patients with COVID-19-related myocarditis with echocardiography and to compare these findings with cardiac magnetic resonance (CMR) results. Patients with confirmed acute myocarditis and age- and gender-matched healthy controls were enrolled. Both patients with COVID-19-related myocarditis and healthy controls underwent standard transthoracic echocardiography and speckle-tracking analysis at the moment of admission and after 6 months of follow-up. The data of 55 patients with myocarditis (mean age 46.4 ± 15.3, 70% males) and 55 healthy subjects were analyzed. The myocarditis group showed a significantly reduced global longitudinal strain (GLS) and sub-epicardial strain, compared to the control (p < 0.001). We found a positive correlation (r = 0.65, p < 0.0001) between total scar burden (TSB) on CMR and LV GLS. After 6 months of follow-up, GLS showed marked improvements in myocarditis patients on optimal medical therapy (p < 0.01). Furthermore, we showed a strong association between baseline GLS, left ventricular ejection fraction (LVEF) and TSB with LVEF at 6 months of follow-up. After a multivariable linear regression analysis, baseline GLS, LVEF and TSB were independent predictors of a functional outcome at follow-up (p < 0.0001). Cardiac function and myocardial longitudinal deformation, assessed by echocardiography, are associated with TSB at CMR and have a predictive value of functional recovery in the follow-up.
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