Evidence map›Paper›PMID 35627201›Full record

ArticleGenes2022

Targeted Sequencing of Candidate Regions Associated with Sagittal and Metopic Nonsyndromic Craniosynostosis.

Cristina M Justice, Anthony M Musolf, Araceli Cuellar, Wanda Lattanzi, Emil Simeonov, Radka Kaneva, Justin Paschall, Michael Cunningham, Andrew O M Wilkie, Alexander F Wilson and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

Cristina M JusticeGenometrics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institute of Health (NIH), Baltimore, MD 21224, USA.
Anthony M MusolfStatistical Genetics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institute of Health (NIH), Baltimore, MD 21224, USA.
Araceli CuellarDepartment of Pediatrics, University of California Davis, Sacramento, CA 95616, USA.
Wanda LattanziFondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0003-3092-4936
Emil SimeonovPediatric Clinic, Alexandrovska University Hospital, Medical University of Sofia, 1431 Sofia, Bulgaria.
Radka KanevaMolecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University of Sofia, 1431 Sofia, Bulgaria.ORCID 0000-0002-1437-1393
Justin PaschallBioinformatics Core, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institute of Health (NIH), Bethesda, MD 20892, USA.
Michael CunninghamSeattle Children's Craniofacial Center, Center of Developmental Biology and Regenerative Medicine and Division of Craniofacial Medicine, Department of Pediatrics, University of Washington, Seattle, WA 98105, USA.
Andrew O M WilkieMRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.
Alexander F WilsonGenometrics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institute of Health (NIH), Baltimore, MD 21224, USA.
Paul A RomittiDepartment of Epidemiology, College of Public Health, The University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0001-5393-9984
Simeon A BoyadjievDepartment of Pediatrics, University of California Davis, Sacramento, CA 95616, USA.
National Human Genome Research Institute · USMedical University of Sofia · BGUniversity of California, Davis · USJohn Radcliffe Hospital · GBSeattle Children's Hospital · USUniversità Cattolica del Sacro Cuore · ITUniversity of Iowa · US

Funding

Genetic Epidemiology of Complex TraitsZIAHG200327 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BAILEY-WILSON, JOAN ELLEN · 2009 to 2022
$10.5M
SINGLE SUTURE CRANIOSYNOSTOSIS: CANDIDATE GENE AND PATHWAY DISCOVERYR01DE018227 · NIDCR · UNIVERSITY OF WASHINGTON · PI CUNNINGHAM, MICHAEL L · 2008 to 2017
$5.6M
NONSYNDROMIC CRANIOSYNOSTOSIS: PHENOTYPE/GENOTYPE STUDYR01DE016886 · NIDCR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BOYADJIEV BOYD, SIMEON A, ROMITTI, PAUL A · 2006 to 2018
$5.5M
CDC HHS U01 DD001223NCBDD CDC HHS U01 DD001223NHGRI NIH HHS HHSN268200782096CNICHD NIH HHS HHSN275201100001CNICHD NIH HHS HHSN275201100001GNICHD NIH HHS HHSN275201100001INIDCR NIH HHS R01 DE016886NIDCR NIH HHS R01 DE018227Wellcome Trust 102731/Z/13/Z
6 · The paper itself

Abstract

Craniosynostosis (CS) is a major birth defect in which one or more skull sutures fuse prematurely. We previously performed a genome-wide association study (GWAS) for sagittal non-syndromic CS (sNCS), identifying associations downstream from

Indexed as

CraniosynostosesGenome-Wide Association StudyAllelesCarrier ProteinsHumansBMPER protein, humanCarrier ProteinsBBS9BMP2BMP7BMPERcraniosynostosismetopicnonsyndromic  non-syndromicsagittaltargeted sequencing

Identifiers

PMID35627201
PMCPMC9141801
OpenAlexW4225302266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.