Evidence map›Paper›PMID 35627151›Full record

ArticleGenes2022

Contradictory Phylogenetic Signals in the Laurasiatheria Anomaly Zone.

Liliya Doronina, Graham M Hughes, Diana Moreno-Santillan, Colleen Lawless, Tadhg Lonergan, Louise Ryan, David Jebb, Bogdan M Kirilenko, Jennifer M Korstian, Liliana M Dávalos and 8 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
9.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 7 countries.

Liliya DoroninaInstitute of Experimental Pathology, ZMBE, University of Münster, 48149 Münster, Germany.ORCID 0000-0002-7170-7084
Graham M HughesSchool of Biology and Environmental Science, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.ORCID 0000-0003-3088-345X
Diana Moreno-SantillanDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.
Colleen LawlessSchool of Biology and Environmental Science, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.ORCID 0000-0002-4454-7994
Tadhg LonerganSchool of Biology and Environmental Science, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.ORCID 0000-0002-3852-0111
Louise RyanSchool of Biology and Environmental Science, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.ORCID 0000-0002-6876-677X
David JebbMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
Bogdan M KirilenkoLOEWE Centre for Translational Biodiversity Genomics, 60325 Frankfurt, Germany.
Jennifer M KorstianDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.
Liliana M DávalosDepartment of Ecology and Evolution and Consortium for Inter-Disciplinary Environmental Research, Stony Brook University, Stony Brook, NY 11794, USA.
Sonja C VernesSchool of Biology, The University of St Andrews, St Andrews KY16 9ST, UK.
Eugene W MyersMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
Emma C TeelingSchool of Biology and Environmental Science, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.
Michael HillerLOEWE Centre for Translational Biodiversity Genomics, 60325 Frankfurt, Germany.ORCID 0000-0003-3024-1449
Lars S JermiinSchool of Biology and Environmental Science, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.
Jürgen SchmitzInstitute of Experimental Pathology, ZMBE, University of Münster, 48149 Münster, Germany.ORCID 0000-0002-4686-861X
Mark S SpringerDepartment of Evolution, Ecology and Organismal Biology, University of California, Riverside, CA 92521, USA.
David A RayDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0002-3340-3987
University College Dublin · IETexas Tech University · USGoethe University Frankfurt · DEUniversity of Münster · DEMax Planck Institute for the Physics of Complex Systems · DEOkinawa Institute of Science and Technology Graduate University · JPStony Brook University · USUniversity of California, Riverside · USUniversity of St Andrews · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Relationships among laurasiatherian clades represent one of the most highly disputed topics in mammalian phylogeny. In this study, we attempt to disentangle laurasiatherian interordinal relationships using two independent genome-level approaches: (1) quantifying retrotransposon presence/absence patterns, and (2) comparisons of exon datasets at the levels of nucleotides and amino acids. The two approaches revealed contradictory phylogenetic signals, possibly due to a high level of ancestral incomplete lineage sorting. The positions of Eulipotyphla and Chiroptera as the first and second earliest divergences were consistent across the approaches. However, the phylogenetic relationships of Perissodactyla, Cetartiodactyla, and Ferae, were contradictory. While retrotransposon insertion analyses suggest a clade with Cetartiodactyla and Ferae, the exon dataset favoured Cetartiodactyla and Perissodactyla. Future analyses of hitherto unsampled laurasiatherian lineages and synergistic analyses of retrotransposon insertions, exon and conserved intron/intergenic sequences might unravel the conflicting patterns of relationships in this major mammalian clade.

Indexed as

EutheriaRetroelementsAnimalsGenomeMammalsPhylogenyRetroelementsanomaly zoneexon coalescenceexon concatenationLaurasiatheriaretrophylogenomicsScrotifera

Identifiers

PMID35627151
PMCPMC9141728
OpenAlexW4225006117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.