ArticleGenes2022
Effect of Zeolite Supplementation on Gene Expression in the Intestinal Mucosa in the Context of Immunosafety Support in Poultry.
Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- A meta-analysis of the effects of clay mineral supplementation on alkaline phosphatase, broiler health, and performance.Poultry science · 2023Pooled it
- Effects of Zeolite on Virulence Gene Content in Avian PathogenicVeterinary medicine international · 2026Article
- Bedding' dry sanitization with aluminosilicates affects its chemical composition, growth performance, meat quality, and footpad dermatitis incidence in broiler chickens.Poultry science · 2025Article
- Halloysite supplemented in the diet, and sex of Cherry Valley ducks affects growth, carcass composition, meat quality, and jejunum and leg bone strength.BMC veterinary research · 2025Article
- Zeolite for preventing periparturient hypocalcemia in dairy cows: mechanisms and application strategies.Frontiers in veterinary science · 2025Review
- The effect of coffee husks used as pellet bedding material on the intestinal barrier, immune-related gene expression and microbiota composition in the broiler chicken caecum.Journal of veterinary research · 2024Article
- Performance and economic efficiency of laying hens in response to adding zeolite to feed and litter.Poultry science · 2024Article
- The effect of oral administration of zeolite on the energy metabolism and reproductive health of Romanian spotted breed in advanced gestation and post partum period.Veterinary and animal science · 2024Article
- Growth performance, meat quality, strength of jejunum and leg bones of both sexes Cherry Valley ducks fed with zeolite.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zeolite is an effective and non-toxic silicate mineral. Its properties are widely used in industry due to its sorption and ion exchange properties. Due to its excellent chemical properties, it has also great potential in poultry production as a food additive or supplement to bedding. This is of great importance for the biosafety and hygiene of production. The study aimed to analyse the effects of simultaneous application of zeolite to feed and bedding on production parameters and expression of genes related to intestinal tightness, organism defence, and immune response. Male Ross 308 broiler chickens were used in the experiment. In the experimental group, an external factor in the form of a powdery zeolite was used for feed and pelleted bedding. On the day of slaughter, the caecal mucosa was collected for gene expression analysis. We showed no significant changes in the tissue composition of the carcasses, but zeolite had a beneficial effect on the carcass yield. The analysis of the immune gene panel showed a significant increase in the expression of the interleukins and interferons genes. We have demonstrated the effect of zeolite on the improvement of the intestinal barrier and increasing the tightness of the intestines. There were no changes in gene expression related to the host's defence against infections; therefore, based on the obtained results, it was concluded that zeolite can be considered an immunomodulating factor of the immune system.
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Registered trials
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