Evidence map›Paper›PMID 35627039›Full record

ArticleFoods (Basel, Switzerland)2022

Curcumin-Loaded Liposome Preparation in Ultrasound Environment under Pressurized Carbon Dioxide.

Wahyudiono, Jiayang He, Xin Hu, Siti Machmudah, Keiji Yasuda, Seiichi Takami, Hideki Kanda, Motonobu Goto

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Liposomes from red betel (Open veterinary journal · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

WahyudionoDepartment of Materials Process Engineering, Nagoya University, Nagoya 464-8603, Japan.
Jiayang HeDepartment of Materials Process Engineering, Nagoya University, Nagoya 464-8603, Japan.
Xin HuDepartment of Materials Process Engineering, Nagoya University, Nagoya 464-8603, Japan.
Siti MachmudahDepartment of Chemical Engineering, Institut Teknologi Sepuluh Nopember, Surabaya 60111, Indonesia.
Keiji YasudaDepartment of Chemical Systems Engineering, Nagoya University, Nagoya 464-8603, Japan.
Seiichi TakamiDepartment of Materials Process Engineering, Nagoya University, Nagoya 464-8603, Japan.
Hideki KandaDepartment of Materials Process Engineering, Nagoya University, Nagoya 464-8603, Japan.ORCID 0000-0002-8393-4276
Motonobu GotoDepartment of Materials Process Engineering, Nagoya University, Nagoya 464-8603, Japan.ORCID 0000-0003-3219-5028

Funding

Japan Science and Technology Agency SICORP (grant number JPMJSC18H1)Japan Society for the Promotion of Science KAKENHI (grant number JP20H02515)
6 · The paper itself

Abstract

Curcumin-loaded liposomes were prepared using a supercritical carbon dioxide (SCCO2)−ultrasound environment system. The experiments were performed at temperatures of 40−70 °C and pressures of 10−25 MPa in a batch system with ultrasonication for 60 min. Transmission electron microscopy (TEM) images revealed liposome products with spherical morphologies and diameters of <100 nm. Dynamic light scattering (DLS) analysis indicated that the curcumin-loaded liposome nanosuspension exhibited good stability. Changing the operating conditions influenced the amount of liposome-encapsulated curcumin; as the operating temperature or pressure increased, the diameter of the liposome products and the amount of liposome-encapsulated curcumin increased and decreased, respectively. Herein, we described an innovative and practical organic-solvent-free method for generating liposomes from phospholipids.

Indexed as

curcuminencapsulationliposomephospholipidsupercritical

Identifiers

PMID35627039
PMCPMC9141155

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.