Evidence map›Paper›PMID 35627022›Full record

ArticleFoods (Basel, Switzerland)2022

The First Optimization Process from Cultivation to Flavonoid-Rich Extract from

Larissa Marina Pereira Silva, Maria Raquel Cavalcanti Inácio, Gualter Guenter Costa da Silva, Jucier Magson de Souza E Silva, Jefferson Romáryo Duarte da Luz, Maria das Graças Almeida, Edgar Perin Moraes, Debora Esposito, Leandro De Santis Ferreira, Silvana Maria Zucolotto

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Effect ofFrontiers in pharmacology · 2025
    Pooled it
  2. Heliyon · 2023
    Article
  3. Metabolites · 2023
    Article
  4. Article
  5. Article
  6. A Relook into the Flavonoid Chemical Space ofJournal of analytical methods in chemistry · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Larissa Marina Pereira SilvaLaboratory of Pharmacognosy, Research Group of Bioactive Natural Products (PNBio), Postgraduate Program in Drug Development and Technological Innovation, Federal University of Rio Grande do Norte, Natal 59012-570, Brazil.ORCID 0000-0002-7480-1412
Maria Raquel Cavalcanti InácioLaboratory of Pharmacognosy, Research Group of Bioactive Natural Products (PNBio), Postgraduate Program in Drug Development and Technological Innovation, Federal University of Rio Grande do Norte, Natal 59012-570, Brazil.
Gualter Guenter Costa da SilvaAgricultural Sciences Unit, Federal University of Rio Grande do Norte, Macaíba 59280-000, Brazil.
Jucier Magson de Souza E SilvaAgricultural Sciences Unit, Federal University of Rio Grande do Norte, Macaíba 59280-000, Brazil.
Jefferson Romáryo Duarte da LuzMultidisciplinary Research Laboratory (LabMult), Department of Clinical and Toxicological Analyzes, Federal University of Rio Grande do Norte, Natal 59012-570, Brazil.ORCID 0000-0002-8249-7617
Maria das Graças AlmeidaMultidisciplinary Research Laboratory (LabMult), Department of Clinical and Toxicological Analyzes, Federal University of Rio Grande do Norte, Natal 59012-570, Brazil.ORCID 0000-0002-5587-0922
Edgar Perin MoraesChemometrics and Biological Chemistry Group (CBC), Institute of Chemistry, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil.
Debora EspositoPlants for Human Health Institute, North Carolina State University, 600 Laureate Way, Kannapolis, NC 28081, USA.ORCID 0000-0001-9689-7622
Leandro De Santis FerreiraLaboratory of Quality Control of Medicines (LCQMed), Department of Pharmacy, Federal University of Rio Grande do Norte, Natal 59012-570, Brazil.ORCID 0000-0002-8408-5886
Silvana Maria ZucolottoLaboratory of Pharmacognosy, Research Group of Bioactive Natural Products (PNBio), Postgraduate Program in Drug Development and Technological Innovation, Federal University of Rio Grande do Norte, Natal 59012-570, Brazil.ORCID 0000-0002-2768-0793
Universidade Federal do Rio Grande do Norte · BRNorth Carolina State University · US

Funding

CAPES-PRInt 88887.575810/2020-00Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) finance code 001research productivity fellow of the CNPq Grant number 313727/2020-1United States Department of Agriculture (USDA) Hatch Project #1016019 (NC02671)
6 · The paper itself

Abstract

Flavonoids are significant antioxidant and anti-inflammatory agents and have multiple potential health applications.

Indexed as

cultivationflavonoidsHPLC-ESI-QTRAP-MS/MSMoringa oleiferaresponse surface methodologyultrasound

Identifiers

PMID35627022
PMCPMC9140588
OpenAlexW4280627415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.