Evidence map›Paper›PMID 35626671›Full record

ArticleCells2022

Distinct Effector Programs of Brain-Homing CD8

Steven C Koetzier, Jamie van Langelaar, Marie-José Melief, Annet F Wierenga-Wolf, Cato E A Corsten, Katelijn M Blok, Cindy Hoeks, Bieke Broux, Beatrijs Wokke, Marvin M van Luijn and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. CD103Nature communications · 2025
    Article
  2. Article
  3. Article
  4. Biological aging in multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2023
    Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Steven C KoetzierDepartment of Immunology, Erasmus MC, University Medical Center Rotterdam, 3000 Rotterdam, The Netherlands.ORCID 0000-0002-7000-9321
Jamie van LangelaarDepartment of Immunology, Erasmus MC, University Medical Center Rotterdam, 3000 Rotterdam, The Netherlands.
Marie-José MeliefDepartment of Immunology, Erasmus MC, University Medical Center Rotterdam, 3000 Rotterdam, The Netherlands.
Annet F Wierenga-WolfDepartment of Immunology, Erasmus MC, University Medical Center Rotterdam, 3000 Rotterdam, The Netherlands.
Cato E A CorstenMS Center ErasMS, Erasmus MC, University Medical Center Rotterdam, 3000 Rotterdam, The Netherlands.ORCID 0000-0001-6531-6979
Katelijn M BlokMS Center ErasMS, Erasmus MC, University Medical Center Rotterdam, 3000 Rotterdam, The Netherlands.ORCID 0000-0001-9530-5023
Cindy HoeksNeuro-Immune Connections and Repair Lab, Department of Immunology and Infection, Biomedical Research Institute, Hasselt University, 3500 Hasselt, Belgium.ORCID 0000-0002-6249-9404
Bieke BrouxNeuro-Immune Connections and Repair Lab, Department of Immunology and Infection, Biomedical Research Institute, Hasselt University, 3500 Hasselt, Belgium.ORCID 0000-0001-8509-2415
Beatrijs WokkeMS Center ErasMS, Erasmus MC, University Medical Center Rotterdam, 3000 Rotterdam, The Netherlands.
Marvin M van LuijnDepartment of Immunology, Erasmus MC, University Medical Center Rotterdam, 3000 Rotterdam, The Netherlands.ORCID 0000-0002-1283-1018
Joost SmoldersDepartment of Immunology, Erasmus MC, University Medical Center Rotterdam, 3000 Rotterdam, The Netherlands.ORCID 0000-0001-9766-8661
Erasmus MC · NLHasselt University · BENetherlands Institute for Neuroscience · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effector programs of CD8

Indexed as

CD8-Positive T-LymphocytesMultiple SclerosisBrainGranzymesHumansT-Box Domain ProteinsGranzymesT-Box Domain Proteinscytotoxicitypre-existing and brain-residencytranscription factors

Identifiers

PMID35626671
PMCPMC9139595
OpenAlexW4280553389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.