ArticleDiagnostics (Basel, Switzerland)2022
Fracture Related Infections and Their Risk Factors for Treatment Failure-A Major Trauma Centre Perspective.
Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Bioelectric warfare on bone infection: The role of piezoelectric biomaterials in osteomyelitis management.Fundamental research · 2026Review
- Article
- Strategic considerations in the treatment of infected nonunion in the lower extremity: a narrative review.International journal of surgery (London, England) · 2026Article
- Investigating long-term quality of life and depressive symptoms following fracture-related infection: a systematic review with meta-analysis of heterogeneous evidence.Journal of bone and joint infection · 2026Review
- Development and evaluation of a risk calculator for fracture-related infection after open reduction and internal fixation: a multi-institutional study.BMC musculoskeletal disorders · 2025Article
- Antibacterial molybdenum disulfide with silver phosphate coating on titanium fixator in rabbit models of rib fracture infection.Journal of thoracic disease · 2025Article
- Combination Antibiotic Therapy for Orthopedic Infections.Antibiotics (Basel, Switzerland) · 2025Review
- Identifying risk factors for systemic complications following fracture-related infection.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- Association between periodontitis and fracture-related infection in patients with severe open fractures of the upper and/or lower extremities.BMC oral health · 2025Article
- Article
- Diagnostic Value of Increased [18F]FDG Uptake in Locoregional Lymph Nodes on PET/CT in Patients with Suspected Fracture-Related Infection.Diagnostics (Basel, Switzerland) · 2025Article
- A Systematic Review and Meta-Analysis of Fracture-Related Infections in Maxillofacial Trauma: Incidence, Risk Factors, and Management Strategies.Journal of clinical medicine · 2025Review
- Article
- Biofilm Formation, Antibiotic Resistance, and Infection (BARI): The Triangle of Death.Journal of clinical medicine · 2024Review
- Fracture-related infections after osteosynthesis for hip fracture are associated with higher mortality: A retrospective single-center cohort study.Acta orthopaedica · 2024Article
- Pathogens in FRI - Do bugs matter? - An analysis of FRI studies to assess your enemy.Journal of orthopaedics · 2024Article
- Variation in North American Infectious Disease Specialists' Practice Regarding Oral and Suppressive Antibiotics for Adult Osteoarticular Infections: Results of an Emerging Infections Network (EIN) Survey.Open forum infectious diseases · 2024Article
- Multisite Study of the Management of Musculoskeletal Infection After Trauma: The MMUSKIT Study.Open forum infectious diseases · 2024Article
- Prevention and treatment of osteomyelitis after open tibia fractures.OTA international : the open access journal of orthopaedic trauma · 2024Review
- [Diagnostic and therapeutic work-up of infected tibial nonunion].Unfallchirurgie (Heidelberg, Germany) · 2024Review
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fracture related infections (FRI) are debilitating and costly complications of musculoskeletal trauma surgery that can result in permanent functional loss or amputation. Surgical treatment can be unsuccessful, and it is necessary to determine the predictive variables associated with FRI treatment failure, allowing one to optimise them prior to treatment and identify patients at higher risk. The clinical database at a major trauma centre was retrospectively reviewed between January 2015 and January 2021. FRI treatment failure was defined by infection recurrence or amputation. A univariable logistic regression analysis was performed, followed by a multivariable regression analysis for significant outcomes between groups on univariable analysis, to determine risk factors for treatment failure. In total, 102 patients were identified with a FRI (35 open, 67 closed fractures). FRI treatment failure occurred in 24 patients (23.5%). Risk factors determined by our multivariate logistic regression model were obesity (OR 2.522; 95% CI, 0.259-4.816;
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