Evidence map›Paper›PMID 35626421›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Utility of Next-Generation Sequencing in the Reconstruction of Clonal Architecture in a Patient with an

Javier Simarro, Gema Pérez-Simó, Nuria Mancheño, Carlos Francisco Muñoz-Núñez, Enrique Cases, Óscar Juan, Sarai Palanca

Open access · goldAbstract readCase Reports
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Javier SimarroMolecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.ORCID 0000-0003-3155-1713
Gema Pérez-SimóMolecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.
Nuria MancheñoPathology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.
Carlos Francisco Muñoz-NúñezRadiology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.
Enrique CasesPulmonology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.
Óscar JuanMedical Oncology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.ORCID 0000-0002-7772-9030
Sarai PalancaMolecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.ORCID 0000-0003-0001-1060
Hospital Universitari i Politècnic La Fe · ESUniversitat de València · ES

Funding

Consellería de Educación, Investigación, Cultura y Deporte de la Comunidad Valenciana ACIF/2018/258Roche Farma IIS La Fe 2015/0713
6 · The paper itself

Abstract

EGFR tyrosine kinase inhibitors (EGFR-TKIs) have revolutionized the treatment of non-small cell lung cancer (NSCLC) patients with activating

Indexed as

EGFR mutationsliquid biopsymolecular diagnosticsnext-generation sequencingnon-small cell lung cancerprecision medicineresistance mechanisms

Identifiers

PMID35626421
PMCPMC9141594
OpenAlexW4280580560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.