Evidence map›Paper›PMID 35626404›Full record

ReviewDiagnostics (Basel, Switzerland)2022

Cardiovascular/Stroke Risk Assessment in Patients with Erectile Dysfunction-A Role of Carotid Wall Arterial Imaging and Plaque Tissue Characterization Using Artificial Intelligence Paradigm: A Narrative Review.

Narendra N Khanna, Mahesh Maindarkar, Ajit Saxena, Puneet Ahluwalia, Sudip Paul, Saurabh K Srivastava, Elisa Cuadrado-Godia, Aditya Sharma, Tomaz Omerzu, Luca Saba and 16 more

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 19 institutions in 8 countries.

Narendra N KhannaDepartment of Cardiology, Indraprastha APOLLO Hospitals, New Delhi 110076, India.
Mahesh MaindarkarDepartment of Biomedical Engineering, North Eastern Hill University, Shillong 793022, India.
Ajit SaxenaDepartment of Urology, Indraprastha APOLLO Hospitals, New Delhi 110076, India.
Puneet AhluwaliaMax Institute of Cancer Care, Max Super Specialty Hospital, New Delhi 110017, India.
Sudip PaulDepartment of Biomedical Engineering, North Eastern Hill University, Shillong 793022, India.ORCID 0000-0001-9856-539X
Saurabh K SrivastavaCollege of Computing Sciences and IT, Teerthanker Mahaveer University, Moradabad 244001, India.
Elisa Cuadrado-GodiaDepartment of Neurology, Hospital del Mar Medical Research Institute, 08003 Barcelona, Spain.ORCID 0000-0002-9147-875X
Aditya SharmaDivision of Cardiovascular Medicine, University of Virginia, Charlottesville, VA 22908, USA.
Tomaz OmerzuDepartment of Neurology, University Medical Centre Maribor, 2000 Maribor, Slovenia.
Luca SabaDepartment of Radiology, University of Cagliari, 09124 Cagliari, Italy.
Sophie MavrogeniCardiology Clinic, Onassis Cardiac Surgery Centre, 176 74 Athens, Greece.ORCID 0000-0003-1089-7766
Monika TurkDepartment of Neurology, University Medical Centre Maribor, 2000 Maribor, Slovenia.
John R LairdHeart and Vascular Institute, Adventist Health St. Helena, St. Helena, CA 94574, USA.
George D KitasAcademic Affairs, Dudley Group NHS Foundation Trust, Dudley DY1 2HQ, UK.
Mostafa FatemiDepartment of Physiology & Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, NY 55905, USA.ORCID 0000-0002-6603-9077
Al Baha BarqawiDivision of Urology, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Martin MinerMen's Health Centre, Miriam Hospital Providence, Providence, RI 02906, USA.
Inder M SinghStroke Monitoring and Diagnostic Division, AtheroPointTM, Roseville, CA 95661, USA.
Amer JohriDepartment of Medicine, Division of Cardiology, Queen's University, Kingston, ON K7L 3N6, Canada.
Mannudeep M KalraDepartment of Radiology, Harvard Medical School, Boston, MA 02115, USA.
Vikas AgarwalSanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.ORCID 0000-0002-4508-1233
Kosmas I ParaskevasDepartment of Vascular Surgery, Central Clinic of Athens, 106 80 Athens, Greece.ORCID 0000-0001-6865-2919
Jagjit S TejiAnn and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Mostafa M FoudaDepartment of Electrical and Computer Engineering, Idaho State University, Pocatello, ID 83209, USA.ORCID 0000-0003-1790-8640
Gyan PareekMinimally Invasive Urology Institute, Brown University, Providence, RI 02912, USA.
Jasjit S SuriStroke Monitoring and Diagnostic Division, AtheroPointTM, Roseville, CA 95661, USA.
North Eastern Hill University · INUniversity Clinical Centre Maribor · SIBrown University · USDudley Group NHS Foundation Trust · GBHarvard University · USHospital Del Mar · ESIdaho State University · USLurie Children's Hospital · USMax Super Speciality Hospital · INMayo Clinic · USOnassis Cardiac Surgery Center · GRProvidence College · USQueen's University · CASanjay Gandhi Post Graduate Institute of Medical Sciences · INSt. Helena Hospital · USTeerthanker Mahaveer University · INUniversity of Cagliari · ITUniversity of Colorado Anschutz Medical Campus · USUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe role of erectile dysfunction (ED) has recently shown an association with the risk of stroke and coronary heart disease (CHD) via the atherosclerotic pathway. Cardiovascular disease (CVD)/stroke risk has been widely understood with the help of carotid artery disease (CTAD), a surrogate biomarker for CHD. The proposed study emphasizes artificial intelligence-based frameworks such as machine learning (ML) and deep learning (DL) that can accurately predict the severity of CVD/stroke risk using carotid wall arterial imaging in ED patients.

methodsUsing the PRISMA model, 231 of the best studies were selected. The proposed study mainly consists of two components: (i) the pathophysiology of ED and its link with coronary artery disease (COAD) and CHD in the ED framework and (ii) the ultrasonic-image morphological changes in the carotid arterial walls by quantifying the wall parameters and the characterization of the wall tissue by adapting the ML/DL-based methods, both for the prediction of the severity of CVD risk. The proposed study analyzes the hypothesis that ML/DL can lead to an accurate and early diagnosis of the CVD/stroke risk in ED patients. Our finding suggests that the routine ED patient practice can be amended for ML/DL-based CVD/stroke risk assessment using carotid wall arterial imaging leading to fast, reliable, and accurate CVD/stroke risk stratification. SUMMARY: We conclude that ML and DL methods are very powerful tools for the characterization of CVD/stroke in patients with varying ED conditions. We anticipate a rapid growth of these tools for early and better CVD/stroke risk management in ED patients.

Indexed as

atherosclerosiscardiovascular diseasecarotid artery diseasecarotid ultrasound-based tissue characterizationdeep learningerectile dysfunctionmachine learningpathophysiologyrisk assessment

Identifiers

PMID35626404
PMCPMC9141739
OpenAlexW4280518754

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.