ArticleDiagnostics (Basel, Switzerland)2022
Improved Image Analysis for Measuring Gastric Ulcer Index in Animal Models and Clinical Diagnostic Data.
Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Therapeutic effects of curcumin on upper gastrointestinal diseases: a systematic review and meta-analysis of animal studies.BMC complementary medicine and therapies · 2025Pooled it
- Syringaldehyde inhibits NFκB-mediated inflammation and apoptosis and activates Nrf2/HO-1 signaling to reduce HCl/ethanol-induced gastric injury.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Cheonggukjang-DerivedMetabolites · 2026Article
- Spinosin Attenuates HCl/Ethanol-Induced Gastric Mucosal Injury by Modulating Oxidative Stress, Inflammation, Apoptosis, and Nrf2/HO-1-Associated Responses.Biomedicines · 2026Article
- Inhibition of microRNA-155 regulates gastric mucosal barrier repair and inflammation by targeting SOCS1 for the treatment of acute gastritis.Scientific reports · 2025Article
- T Helper and Cytotoxic T Cells Play an Important Role in Acute Gastric Injury.Diseases (Basel, Switzerland) · 2025Article
- Assessment of sinapic acid's protective effects against ethanol-induced gastric ulcers in rats.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Article
- Gastroprotective Efficacy of North African Medicinal Plants: A Review on Their Therapeutic Potential for Peptic Ulcers.Food science & nutrition · 2024Review
- Gastroprotective Effects of Betahistine Against an Indomethacin-Induced Gastric Mucosal Ulcer in Rats: The Role of CINC-2α Gene.Medical journal of the Islamic Republic of Iran · 2024Article
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Authors and funding
5 authors.
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Abstract
Gastric ulcers are one of the most common gastrointestinal diseases. In this study, as an attempt to reduce the minimal error in clinical observations during the diagnosis of gastric ulcers, the applicability of improved ImageJ analysis (IA) was investigated by comparing the results of animal experiments and clinical data. As a result, IA exhibited a significantly improved potential for determining the ulcer index (UI) of clinical data sheets compared to those rated directly by conventional clinical observation (CCO). This indicated that IA enhanced the reproducibility of the measurement of gastric UI using a Bland-Altman plot, resulting in a reduced deviation of each UI value. In addition, it was confirmed that errors in gastric UI decisions can be reduced by adjusting RGB values in diagnostic clinical data (i.e., adjusting to 100 is relatively better than adjusting to 50 or 200). Together, these results suggest that the new enhanced IA could be compatible with novel applications for measuring and evaluating gastric ulcers in clinical settings, meaning that the developed method could be used not only as an auxiliary tool for CCO, but also as a pipeline for ulcer diagnosis.
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