Evidence map›Paper›PMID 35626261›Full record

ReviewDiagnostics (Basel, Switzerland)2022

Indications, Detection, Completion and Retention Rates of Capsule Endoscopy in Two Decades of Use: A Systematic Review and Meta-Analysis.

Pablo Cortegoso Valdivia, Karolina Skonieczna-Żydecka, Alfonso Elosua, Martina Sciberras, Stefania Piccirelli, Maria Rullan, Trevor Tabone, Katarzyna Gawel, Adam Stachowski, Artur Lemiński and 7 more

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07445828 (Evaluation of Capsule Colonoscopy in Patients With Lynch Syndrome), which is not on this map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07445828 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of Capsule Colonoscopy in Patients With Lynch Syndrome

Typeobservational_patient_registrySponsorRegion SkaneRan2026 to 2029Enrolled78ConditionsLynch SyndromeArmscolon capsule endoscopy
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 6 countries.

Pablo Cortegoso ValdiviaGastroenterology and Endoscopy Unit, University Hospital of Parma, University of Parma, 43126 Parma, Italy.ORCID 0000-0002-8793-5890
Karolina Skonieczna-ŻydeckaDepartment of Biochemical Sciences, Pomeranian Medical University, 71-460 Szczecin, Poland.ORCID 0000-0002-3430-9079
Alfonso ElosuaGastroenterology Unit, Hospital García Orcoyen, 31200 Estella, Spain.ORCID 0000-0001-6097-7612
Martina SciberrasDivision of Gastroenterology, Mater Dei Hospital, MSD 2080 Msida, Malta.
Stefania PiccirelliDigestive Endoscopy Unit and Gastroenterology, Fondazione Poliambulanza, 25124 Brescia, Italy.
Maria RullanGastroenterology Unit, Hospital García Orcoyen, 31200 Estella, Spain.ORCID 0000-0001-7413-2194
Trevor TaboneDivision of Gastroenterology, Mater Dei Hospital, MSD 2080 Msida, Malta.
Katarzyna GawelDepartment of Gastroenterology, Pomeranian Medical University, 70-001 Szczecin, Poland.
Adam StachowskiDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University, 70-001 Szczecin, Poland.
Artur LemińskiDepartment of Urology and Urological Oncology, Pomeranian Medical University, 70-001 Szczecin, Poland.ORCID 0000-0003-1446-2970
Wojciech MarliczDepartment of Gastroenterology, Pomeranian Medical University, 70-001 Szczecin, Poland.ORCID 0000-0002-2649-5967
Ignacio Fernández-UriénDepartment of Gastroenterology, University Hospital of Navarra, 31008 Pamplona, Spain.
Pierre EllulDivision of Gastroenterology, Mater Dei Hospital, MSD 2080 Msida, Malta.
Cristiano SpadaDigestive Endoscopy Unit and Gastroenterology, Fondazione Poliambulanza, 25124 Brescia, Italy.ORCID 0000-0002-5692-0960
Marco PennazioUniversity Division of Gastroenterology, City of Health and Science University Hospital, University of Turin, 10126 Turin, Italy.
Ervin TothDepartment of Gastroenterology, Skåne University Hospital, Lund University, 20502 Malmö, Sweden.ORCID 0000-0002-9314-9239
Anastasios KoulaouzidisDepartment of Medicine, OUH Svendborg Sygehus, 5700 Svendborg, Denmark.ORCID 0000-0002-2248-489X
Pomeranian Medical University · PLMater Dei Hospital · MTUniversità Cattolica del Sacro Cuore · ITLund University · SEUniversidad de Navarra · ESUniversity of Parma · ITUniversity of Southern Denmark · DKUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCapsule endoscopy (CE) has become a widespread modality for non-invasive evaluation of the gastrointestinal (GI) tract, with several CE models having been developed throughout the years. The aim of this systematic review and meta-analysis is to evaluate performance measures such as completion, detection and retention rates of CE.

methodsLiterature through to August 2021 was screened for articles regarding all capsule types: small bowel, double-headed capsule for the colon or PillCam

results328 original articles involving 86,930 patients who underwent CE were included. OGIB was the most common indication (n = 44,750), followed by CS (n = 17,897), CD (n = 11,299), NL (n = 4989) and CeD (n = 947). The most used capsule type was small bowel CE in 236 studies. DR, CR and RR for all indications were 59%, 89.6% and 2%, respectively. According to specific indications: DR were 55%, 66%, 63%, 52% and 62%; CR were 90.6%, 86.5%, 78.2%, 94% and 92.8%; and RR were 2%, 4%, 1%, 6% and 2%.

conclusionsPooled DR, CR and RR are acceptable for all capsule types. OGIB is the most common indication for CE. Technological advancements have expanded the scope of CE devices in detecting GI pathology with acceptable rates for a complete examination.

Indexed as

capsule endoscopycompletiondetectionindicationssystematic review

Identifiers

PMID35626261
PMCPMC9139699
OpenAlexW4282928027

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.