Evidence map›Paper›PMID 35626256›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Combining Optical Coherence Tomography and Fundus Photography to Improve Glaucoma Screening.

Tomoyuki Watanabe, Yoshimune Hiratsuka, Yoshiyuki Kita, Hiroshi Tamura, Ryo Kawasaki, Tetsuji Yokoyama, Motoko Kawashima, Tadashi Nakano, Masakazu Yamada

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tomoyuki WatanabeDepartment of Ophthalmology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
Yoshimune HiratsukaDepartment of Ophthalmology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.ORCID 0000-0001-8934-9396
Yoshiyuki KitaDepartment of Ophthalmology, Kyorin University School of Medicine, Tokyo 181-8611, Japan.
Hiroshi TamuraDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.ORCID 0000-0002-7740-2732
Ryo KawasakiArtificial Intelligence Center for Medical Research and Application, Osaka University Hospital, Suita 565-0871, Japan.ORCID 0000-0002-7492-6303
Tetsuji YokoyamaDepartment of Health Promotion, National Institute of Public Health, Wako 351-0197, Japan.
Motoko KawashimaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Tadashi NakanoDepartment of Ophthalmology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.ORCID 0000-0002-3184-1991
Masakazu YamadaDepartment of Ophthalmology, Kyorin University School of Medicine, Tokyo 181-8611, Japan.

Funding

the Ministry of Health, Labor and Welfare, Japan 19FA1010
6 · The paper itself

Abstract

We aimed to evaluate the accuracy of glaucoma screening using fundus photography combined with optical coherence tomography and determine the agreement between ophthalmologists and ophthalmology residents. We used a comprehensive ophthalmologic examination dataset obtained from 503 cases (1006 eyes). Of the 1006 eyes, 132 had a confirmed glaucoma diagnosis. Overall, 24 doctors, comprising two groups (ophthalmologists and ophthalmology residents, 12 individuals/group), analyzed the data presented in three screening strategies as follows: (1) fundus photography alone, (2) fundus photography + optical coherence tomography, and (3) fundus photography + optical coherence tomography + comprehensive examination. We investigated the diagnostic accuracy (sensitivity and specificity). The respective sensitivity and specificity values for the diagnostic accuracy obtained by 24 doctors, 12 ophthalmologists, and 12 ophthalmology residents were as follows: (1) fundus photography: sensitivity, 55.4%, 55.4%, and 55.4%; specificity, 91.8%, 94.0%, and 89.6%; (2) fundus photography + OCT: sensitivity, 80.0%, 82.3%, and 77.8%; specificity, 91.7%, 92.9%, and 90.6%; and (3) fundus photography + OCT + comprehensive examination: sensitivity 78.4%, 79.8%, and 77.1%; specificity, 92.7%, 94.0%, and 91.3%. The diagnostic accuracy of glaucoma screening significantly increased with optical coherence tomography. Following its addition, ophthalmologists could more effectively improve the diagnostic accuracy than ophthalmology residents. Screening accuracy is improved when optical coherence tomography is added to fundus photography.

Indexed as

diagnostic accuracyglaucomaophthalmologistoptical coherence tomographyscreening

Identifiers

PMID35626256
PMCPMC9139676

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.