Evidence map›Paper›PMID 35626243›Full record

ReviewDiagnostics (Basel, Switzerland)2022

Molecular Diagnostic Review of Diffuse Large B-Cell Lymphoma and Its Tumor Microenvironment.

Robert Ta, David Yang, Christian Hirt, Thomas Drago, Richard Flavin

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Design and synthesis of novelFuture medicinal chemistry · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robert TaMassachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-2204-1810
David YangBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Christian HirtBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Thomas DragoDepartment of Histopathology, St. James's Hospital and Trinity College, D08 NHY1 Dublin, Ireland.
Richard FlavinDepartment of Histopathology, St. James's Hospital and Trinity College, D08 NHY1 Dublin, Ireland.ORCID 0000-0002-4993-4563

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma. It is a clinically and morphologically heterogeneous entity that has continued to resist complete subtyping. Molecular subtyping efforts emerged in earnest with the advent of gene expression profiling (GEP). This molecular subtyping approach has continued to evolve simultaneously with others including immunohistochemistry and more modern genomic approaches. Recently, the veritable explosion of genomic data availability and evolving computational methodologies have provided additional avenues, by which further understanding and subclassification of DBLCLs is possible. The goal of this review is to provide a historical overview of the major classification timepoints in the molecular subtyping of DLBCL, from gene expression profiling to present day understanding.

Indexed as

cell-of-origincytogenetics/FISHdiagnosticsdiffuse large B-cell lymphomagene expression profilingimmunohistochemistryminimum criteria for diagnosismolecular

Identifiers

PMID35626243
PMCPMC9139291

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.