Evidence map›Paper›PMID 35626142›Full record

ReviewCancers2022

Imaging Modalities for Early Detection of Pancreatic Cancer: Current State and Future Research Opportunities.

Katherina P Farr, Daniel Moses, Koroush S Haghighi, Phoebe A Phillips, Claudia M Hillenbrand, Boon H Chua

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Economic evaluations of early detection strategies for pancreatic cancer: a systematic review.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Scientific reports · 2026
    Article
  7. Review
  8. Catching pancreatic cancer early: Are we there yet?Journal of the National Cancer Center · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katherina P FarrSchool of Clinical Medicine, Faculty of Medicine & Health, UNSW, Sydney, NSW 2052, Australia.
Daniel MosesGraduate School of Biomedical Engineering, UNSW, Sydney, NSW 2052, Australia.
Koroush S HaghighiSchool of Clinical Medicine, Faculty of Medicine & Health, UNSW, Sydney, NSW 2052, Australia.
Phoebe A PhillipsPancreatic Cancer Translational Research Group, School of Clinical Medicine, Lowy Cancer Research Centre, UNSW, Sydney, NSW 2052, Australia.
Claudia M HillenbrandResearch Imaging NSW, Division of Research & Enterprise, UNSW, Sydney, NSW 2052, Australia.
Boon H ChuaSchool of Clinical Medicine, Faculty of Medicine & Health, UNSW, Sydney, NSW 2052, Australia.ORCID 0000-0002-7561-7174

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer, one of the most lethal malignancies, is increasing in incidence. While survival rates for many cancers have improved dramatically over the last 20 years, people with pancreatic cancer have persistently poor outcomes. Potential cure for pancreatic cancer involves surgical resection and adjuvant therapy. However, approximately 85% of patients diagnosed with pancreatic cancer are not suitable for potentially curative therapy due to locally advanced or metastatic disease stage. Because of this stark survival contrast, any improvement in early detection would likely significantly improve survival of patients with pancreatic cancer through earlier intervention. This comprehensive scoping review describes the current evidence on groups at high risk for developing pancreatic cancer, including individuals with inherited predisposition, pancreatic cystic lesions, diabetes, and pancreatitis. We review the current roles of imaging modalities focusing on early detection of pancreatic cancer. Additionally, we propose the use of advanced imaging modalities to identify early, potentially curable pancreatic cancer in high-risk cohorts. We discuss innovative imaging techniques for early detection of pancreatic cancer, but its widespread application requires further investigation and potentially a combination with other non-invasive biomarkers.

Indexed as

early detectionMRIpancreatic cancerpancreatic cystic lesionspancreatic ductal adenocarcinomaradiomicsscreening

Identifiers

PMID35626142
PMCPMC9139708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.