Evidence map›Paper›PMID 35626084›Full record

ArticleCancers2022

Predictors of Outcome after (Chemo)Radiotherapy for Node-Positive Oropharyngeal Cancer: The Role of Functional MRI.

Pasqualina D'Urso, Alessia Farneti, Laura Marucci, Simona Marzi, Francesca Piludu, Antonello Vidiri, Giuseppe Sanguineti

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Pasqualina D'UrsoDepartment of Radiotherapy, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Alessia FarnetiDepartment of Radiotherapy, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Laura MarucciDepartment of Radiotherapy, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Simona MarziMedical Physics Laboratory, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.ORCID 0000-0002-9845-4400
Francesca PiluduRadiology and Diagnostic Imaging Department, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Antonello VidiriRadiology and Diagnostic Imaging Department, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Giuseppe SanguinetiDepartment of Radiotherapy, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

Italian Association for Cancer Research 17028
6 · The paper itself

Abstract

The prognosis of a subset of patients with locally advanced oropharyngeal cancer (LA-OPC) is still poor despite improvements in patient selection and treatment. Identifying specific patient- and tumor-related factors can help to select those patients who need intensified treatment. We aimed to assess the role of historical risk factors and novel magnetic resonance imaging (MRI) biomarkers in predicting outcomes in these patients. Patients diagnosed with LA-OPC were studied with diffusion-weighted imaging (DWI) and dynamic-contrast enhanced MRI at baseline and at the 10th radiotherapy (RT) fraction. Clinical information was collected as well. The endpoint of the study was the development of disease progression, locally or distantly. Of the 97 patients enrolled, 68 were eligible for analysis. Disease progression was recorded in 21 patients (11 had loco-regional progression, 10 developed distant metastases). We found a correlation between N diameter and disease control (

Indexed as

chemoradiotherapyDCE-MRIDWIoropharyngeal cancer

Identifiers

PMID35626084
PMCPMC9139324
OpenAlexW4280579901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.