Evidence map›Paper›PMID 35626075›Full record

ArticleCancers2022

Risk of Complications in Patients Undergoing Completion Thyroidectomy after Hemithyroidectomy for Thyroid Nodule with Indeterminate Cytology: An Italian Multicentre Retrospective Study.

Gian Luigi Canu, Fabio Medas, Federico Cappellacci, Alessio Biagio Filippo Giordano, Angela Gurrado, Claudio Gambardella, Giovanni Docimo, Francesco Feroci, Giovanni Conzo, Mario Testini and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  12. Optimal Surgical Approaches for Thyroid Cancer: A Comparative Analysis of Efficacy and Complications.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  13. Regeneration of Thyroid Glands in the Spleen Restores Homeostasis in Thyroidectomy Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Gian Luigi CanuDepartment of Surgical Sciences, University of Cagliari, 09042 Monserrato, CA, Italy.ORCID 0000-0003-3233-0269
Fabio MedasDepartment of Surgical Sciences, University of Cagliari, 09042 Monserrato, CA, Italy.ORCID 0000-0002-9546-0178
Federico CappellacciDepartment of Surgical Sciences, University of Cagliari, 09042 Monserrato, CA, Italy.
Alessio Biagio Filippo GiordanoDepartment of General and Oncologic Surgery, Santo Stefano Hospital, 59100 Prato, PO, Italy.ORCID 0000-0002-9505-791X
Angela GurradoDepartment of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", 70124 Bari, BA, Italy.
Claudio GambardellaDepartment of Medical and Advanced Surgical Sciences, University of Campania "Luigi Vanvitelli", 80131 Naples, NA, Italy.ORCID 0000-0003-2277-2960
Giovanni DocimoDepartment of Medical and Advanced Surgical Sciences, University of Campania "Luigi Vanvitelli", 80131 Naples, NA, Italy.
Francesco FerociDepartment of General and Oncologic Surgery, Santo Stefano Hospital, 59100 Prato, PO, Italy.
Giovanni ConzoDepartment of Traslational Medical Sciences, University of Campania "Luigi Vanvitelli", 80131 Naples, NA, Italy.
Mario TestiniDepartment of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", 70124 Bari, BA, Italy.ORCID 0000-0002-9297-4894
Pietro Giorgio CalòDepartment of Surgical Sciences, University of Cagliari, 09042 Monserrato, CA, Italy.ORCID 0000-0001-9637-1145
University of Cagliari · ITUniversity of Campania "Luigi Vanvitelli" · ITHospital of Prato · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is still controversy as to whether patients undergoing a completion thyroidectomy after a hemithyroidectomy for a thyroid nodule with an indeterminate cytology have a comparable, increased or decreased risk of complications compared to those submitted to primary thyroid surgery. The main aim of this study was to investigate this topic. Patients undergoing a thyroidectomy for thyroid nodular disease with an indeterminate cytology in four high-volume thyroid surgery centres in Italy, between January 2017 and December 2020, were retrospectively analysed. Based on the surgical procedure performed, four groups were identified: the TT Group (total thyroidectomy), HT Group (hemithyroidectomy), CT Group (completion thyroidectomy) and HT + CT Group (hemithyroidectomy with subsequent completion thyroidectomy). A total of 751 patients were included. As for the initial surgery, 506 (67.38%) patients underwent a total thyroidectomy and 245 (32.62%) a hemithyroidectomy. Among all patients submitted to a hemithyroidectomy, 66 (26.94%) were subsequently submitted to a completion thyroidectomy. No statistically significant difference was found in terms of complications comparing both the TT Group with the HT + CT Group and the HT Group with the CT Group. The risk of complications in patients undergoing a completion thyroidectomy after a hemithyroidectomy for a thyroid nodule with an indeterminate cytology was comparable to that of patients submitted to primary thyroid surgery (both a total thyroidectomy and hemithyroidectomy).

Indexed as

completion thyroidectomycomplicationsdifferentiated thyroid carcinomahemithyroidectomyindeterminate thyroid noduletotal thyroidectomy

Identifiers

PMID35626075
PMCPMC9139447
OpenAlexW4280520111

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.