Evidence map›Paper›PMID 35626059›Full record

ReviewCancers2022

Designing the Surface Chemistry of Inorganic Nanocrystals for Cancer Imaging and Therapy.

Fanny Delille, Yuzhou Pu, Nicolas Lequeux, Thomas Pons

Abstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Linking In Vivo Imaging to Therapeutic Outcome withInternational journal of molecular sciences · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fanny DelilleLaboratoire de Physique et d'Etude des Matériaux, Ecole Supérieure de Physique et Chimie Industrielle, Université PSL (Paris Sciences & Lettres), Centre National de Recherche Scientifique, 75005 Paris, France.
Yuzhou PuLaboratoire de Physique et d'Etude des Matériaux, Ecole Supérieure de Physique et Chimie Industrielle, Université PSL (Paris Sciences & Lettres), Centre National de Recherche Scientifique, 75005 Paris, France.ORCID 0000-0001-9897-5196
Nicolas LequeuxLaboratoire de Physique et d'Etude des Matériaux, Ecole Supérieure de Physique et Chimie Industrielle, Université PSL (Paris Sciences & Lettres), Centre National de Recherche Scientifique, 75005 Paris, France.ORCID 0000-0001-7915-2362
Thomas PonsLaboratoire de Physique et d'Etude des Matériaux, Ecole Supérieure de Physique et Chimie Industrielle, Université PSL (Paris Sciences & Lettres), Centre National de Recherche Scientifique, 75005 Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inorganic nanocrystals, such as gold, iron oxide and semiconductor quantum dots, offer promising prospects for cancer diagnostics, imaging and therapy, due to their specific plasmonic, magnetic or fluorescent properties. The organic coating, or surface ligands, of these nanoparticles ensures their colloidal stability in complex biological fluids and enables their functionalization with targeting functions. It also controls the interactions of the nanoparticle with biomolecules in their environment. It therefore plays a crucial role in determining nanoparticle biodistribution and, ultimately, the imaging or therapeutic efficiency. This review summarizes the various strategies used to develop optimal surface chemistries for the in vivo preclinical and clinical application of inorganic nanocrystals. It discusses the current understanding of the influence of the nanoparticle surface chemistry on its colloidal stability, interaction with proteins, biodistribution and tumor uptake, and the requirements to develop an optimal surface chemistry.

Indexed as

cancer imaginggoldiron oxidenanoparticlequantum dotsurface chemistrytherapy

Identifiers

PMID35626059
PMCPMC9139368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.