Evidence map›Paper›PMID 35626045›Full record

ReviewCancers2022

A Systematic Review of the Guidelines on Venous Thromboembolism Prophylaxis in Gynecologic Oncology.

Federico Romano, Giovanni Di Lorenzo, Guglielmo Stabile, Mariateresa Mirandola, Stefano Restaino, Patrizia Ianniello, Giuseppe Mirenda, Giuseppe Ricci

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Direct Oral Anti-Coagulants Continue to Bud into Gynecological Cancer-Thrombosis Prevention.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Federico RomanoInstitute for Maternal and Child Health, IRCCS Burlo Garofolo, Via dell' Istria 65/1, 34137 Trieste, Italy.ORCID 0000-0003-2157-8330
Giovanni Di LorenzoInstitute for Maternal and Child Health, IRCCS Burlo Garofolo, Via dell' Istria 65/1, 34137 Trieste, Italy.
Guglielmo StabileInstitute for Maternal and Child Health, IRCCS Burlo Garofolo, Via dell' Istria 65/1, 34137 Trieste, Italy.ORCID 0000-0001-9266-3896
Mariateresa MirandolaDepartment of Medicine, Surgery and Health Sciences, University of Trieste, Strada di Fiume 447, 34127 Trieste, Italy.
Stefano RestainoDepartment of Maternal and Child Health, University-Hospital of Udine, P.le S. Maria della Misericordia 15, 33100 Udine, Italy.ORCID 0000-0002-7848-0329
Patrizia IannielloDepartment of Medicine, Surgery and Health Sciences, University of Trieste, Strada di Fiume 447, 34127 Trieste, Italy.
Giuseppe MirendaInstitute for Maternal and Child Health, IRCCS Burlo Garofolo, Via dell' Istria 65/1, 34137 Trieste, Italy.
Giuseppe RicciInstitute for Maternal and Child Health, IRCCS Burlo Garofolo, Via dell' Istria 65/1, 34137 Trieste, Italy.ORCID 0000-0002-8031-1102
IRCCS Materno Infantile Burlo Garofolo · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: This review aimed to summarize the indications for venous thromboembolic (VTE) events' prophylaxis in a gynecological cancer population, according to the most recent guidelines. (2) Methods: A systematic review of the guidelines in PubMed, SCOPUS, Web of Science, EMBASE, and CINHAL regarding VTE prevention in gynecological cancer patients was conducted according to PRISMA criteria. We compared the recommendations given by oncological and hematological societies regarding VTE prevention in gynecological cancer patients published from January 2010 through March 2021. We searched for the following keywords: "venous thromboembolism prevention", "cancer", and "guidelines". The AGREE II checklist was used to critically analyze the guidelines' quality. (3) Results: There were 1003 documents available; 14 met the inclusion criteria, 5 were excluded and, eventually, the guidelines of 10 societies were evaluated. (4) Conclusions: The guidelines agree that low-molecular-weight heparin (LMWH) and fondaparinux achieve better results in VTE prevention in gynecological cancer patients. Direct oral anticoagulants (DOACs) can be used to prevent VTE in outpatients and high-risk medical patients after discharge. VTE risk scores should be applied to all oncological patients to identify those who would benefit from a prevention program. More attention should be paid to mechanical prophylactic methods due to the high bleeding risk of gynecological cancer patients.

Indexed as

deep vein thrombosisgynecological cancerpulmonary embolismthromboprophylaxisvenous thromboembolism prevention

Identifiers

PMID35626045
PMCPMC9139174
OpenAlexW4280624913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.