Evidence map›Paper›PMID 35625980›Full record

ReviewCancers2022

In Vitro and In Vivo Anticancer Activity of Basil (

Simone Perna, Hajar Alawadhi, Antonella Riva, Pietro Allegrini, Giovanna Petrangolini, Clara Gasparri, Tariq A Alalwan, Mariangela Rondanelli

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Ethnobotany, Phytochemistry, and Pharmacological Activities ofInternational journal of molecular sciences · 2026
    Pooled it
  2. Article
  3. Article
  4. Primary Metabolites in ThreeLife (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Efficacy ofMicroorganisms · 2025
    Article
  9. Amino Acid Analysis and Cytotoxicity Study of IraqiMolecules (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Bioprospecting of FivePharmaceuticals (Basel, Switzerland) · 2023
    Article
  17. Article
  18. An Update on the Therapeutic Anticancer Potential ofMolecules (Basel, Switzerland) · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Simone PernaDepartment of Biology, College of Science, University of Bahrain, Sakhir Campus, Zallaq P.O. Box 32038, Bahrain.ORCID 0000-0002-2720-1473
Hajar AlawadhiDepartment of Biology, College of Science, University of Bahrain, Sakhir Campus, Zallaq P.O. Box 32038, Bahrain.ORCID 0000-0001-7815-8615
Antonella RivaDevelopment Department, Indena SpA, 20139 Milan, Italy.ORCID 0000-0003-2819-943X
Pietro AllegriniDevelopment Department, Indena SpA, 20139 Milan, Italy.ORCID 0000-0002-4380-9577
Giovanna PetrangoliniDevelopment Department, Indena SpA, 20139 Milan, Italy.ORCID 0000-0001-6681-7329
Clara GasparriEndocrinology and Nutrition Unit, Azienda di Servizi alla Persona ''Istituto Santa Margherita'', University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-1088-6648
Tariq A AlalwanDepartment of Biology, College of Science, University of Bahrain, Sakhir Campus, Zallaq P.O. Box 32038, Bahrain.ORCID 0000-0002-7693-4542
Mariangela RondanelliIRCCS Mondino Foundation, 27100 Pavia, Italy.ORCID 0000-0001-8336-4851
Indena (Italy) · ITUniversity of Bahrain · BHUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer is an irregular proliferation of cells that starts with a gene mutation that alters cellular function, is triggered by several factors, and can be inherited or acquired. The aim of this review is to discuss the anticancer activity of basil and its components' strength, focusing on its implication in cancer prevention and treatment.

methodsThis systematic review involves all of the studies published from 1 January 2010 through 1 January 2022.

resultsIn this review, 16 research articles are included to discuss the potential anticancer ability of the extracts of various

conclusionsBased on 16 published studies, basil demonstrates important anticancer activities in vivo and vitro models, and it could act as a potential cancer.

Indexed as

anticancerantioxidant activityapoptosisbasil extract

Identifiers

PMID35625980
PMCPMC9139360
OpenAlexW4280509944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.