Evidence map›Paper›PMID 35625904›Full record

ReviewBiomedicines2022

Inflammatory Mechanisms of Diabetes and Its Vascular Complications.

Lyudmila V Nedosugova, Yuliya V Markina, Leyla A Bochkareva, Irina A Kuzina, Nina A Petunina, Irina Y Yudina, Tatiana V Kirichenko

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 94 citations in OpenAlex.

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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lyudmila V NedosugovaSechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Yuliya V MarkinaPetrovsky National Research Center of Surgery, 119991 Moscow, Russia.ORCID 0000-0002-3781-6340
Leyla A BochkarevaSechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Irina A KuzinaSechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.ORCID 0000-0001-7923-4894
Nina A PetuninaSechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Irina Y YudinaSechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Tatiana V KirichenkoPetrovsky National Research Center of Surgery, 119991 Moscow, Russia.ORCID 0000-0002-2899-9202
Sechenov University · RUNational Medical Research Center of Cardiology · RURussian Scientific Center of Surgery · RU

Funding

Russian Science Foundation 22-25-00149
6 · The paper itself

Abstract

The main cause of death in patients with type 2 DM is cardiovascular complications resulting from the progression of atherosclerosis. The pathophysiology of the association between diabetes and its vascular complications is complex and multifactorial and closely related to the toxic effects of hyperglycemia that causes increased generation of reactive oxygen species and promotes the secretion of pro-inflammatory cytokines. Subsequent oxidative stress and inflammation are major factors of the progression of type 2 DM and its vascular complications. Data on the pathogenesis of the development of type 2 DM and associated cardiovascular diseases, in particular atherosclerosis, open up broad prospects for the further development of new diagnostic and therapeutic approaches.

Indexed as

cytokinesdiabetesinflammationinsulin resistancemacrophagesmitochondria

Identifiers

PMID35625904
PMCPMC9138517
OpenAlexW4280567357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.