Evidence map›Paper›PMID 35625731›Full record

ArticleBiomedicines2022

Repetitive Transcranial Magnetic Stimulation (rTMS) of Dorsolateral Prefrontal Cortex May Influence Semantic Fluency and Functional Connectivity in Fronto-Parietal Network in Mild Cognitive Impairment (MCI).

Sabrina Esposito, Francesca Trojsi, Giovanni Cirillo, Manuela de Stefano, Federica Di Nardo, Mattia Siciliano, Giuseppina Caiazzo, Domenico Ippolito, Dario Ricciardi, Daniela Buonanno and 11 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 6 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 6 syntheses or guidelines pooled it, 53 citations in OpenAlex.

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  16. Neuropsychiatric symptoms in Alzheimer's disease: Bridging mechanisms, management, and emerging innovations.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 3 institutions in 1 country.

Sabrina EspositoFirst Division of Neurology, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0003-0853-3461
Francesca TrojsiFirst Division of Neurology, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0002-3790-8018
Giovanni CirilloDivision of Human Anatomy, Laboratory of Morphology of Neuronal Networks & Systems Biology, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0003-3183-8773
Manuela de StefanoFirst Division of Neurology, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.
Federica Di NardoDepartment of Advanced Medical and Surgical Sciences, MRI Research Center SUN-FISM, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.
Mattia SicilianoDepartment of Advanced Medical and Surgical Sciences, MRI Research Center SUN-FISM, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0001-5246-2109
Giuseppina CaiazzoDepartment of Advanced Medical and Surgical Sciences, MRI Research Center SUN-FISM, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.
Domenico IppolitoFirst Division of Neurology, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.
Dario RicciardiFirst Division of Neurology, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0003-4862-4165
Daniela BuonannoFirst Division of Neurology, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.
Danilo AtripaldiDepartment of Advanced Medical and Surgical Sciences, MRI Research Center SUN-FISM, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.
Roberta PepeDepartment of Advanced Medical and Surgical Sciences, MRI Research Center SUN-FISM, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.
Giulia D'AlvanoFirst Division of Neurology, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.
Antonella MangioneDepartment of Advanced Medical and Surgical Sciences, MRI Research Center SUN-FISM, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.
Simona BonavitaDepartment of Advanced Medical and Surgical Sciences, MRI Research Center SUN-FISM, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0002-8561-9720
Gabriella SantangeloDepartment of Psychology, University of Campania Luigi Vanvitelli, 81100 Caserta, Italy.
Alessandro IavaroneNeurological Unit, CTO Hospital, AORN Ospedali Dei Colli, 80131 Naples, Italy.
Mario CirilloDepartment of Advanced Medical and Surgical Sciences, MRI Research Center SUN-FISM, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0001-5350-7700
Fabrizio EspositoDepartment of Advanced Medical and Surgical Sciences, MRI Research Center SUN-FISM, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.
Sandro SorbiIRCCS Fondazione Don Carlo Gnocchi ONLUS, 50143 Florence, Italy.
Gioacchino TedeschiFirst Division of Neurology, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.
University of Campania "Luigi Vanvitelli" · ITCTO Hospital · ITDon Carlo Gnocchi Foundation · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive neuromodulation technique that is increasingly used as a nonpharmacological intervention against cognitive impairment in Alzheimer's disease (AD) and other dementias. Although rTMS has been shown to modify cognitive performances and brain functional connectivity (FC) in many neurological and psychiatric diseases, there is still no evidence about the possible relationship between executive performances and resting-state brain FC following rTMS in patients with mild cognitive impairment (MCI). In this preliminary study, we aimed to evaluate the possible effects of rTMS of the bilateral dorsolateral prefrontal cortex (DLPFC) in 27 MCI patients randomly assigned to two groups: one group received high-frequency (10 Hz) rTMS (HF-rTMS) for four weeks (

Indexed as

brain networksmild cognitive impairmentresting state functional MRIrTMS

Identifiers

PMID35625731
PMCPMC9138229
OpenAlexW4224442060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.