Evidence map›Paper›PMID 35625719›Full record

ArticleBiomedicines2022

Characterization of the Upper Respiratory Bacterial Microbiome in Critically Ill COVID-19 Patients.

Xiangning Bai, Aswathy Narayanan, Magdalena Skagerberg, Rafael Ceña-Diez, Christian G Giske, Kristoffer Strålin, Anders Sönnerborg

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Association of nasopharyngealMicrobiology spectrum · 2026
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  11. The nasopharyngeal microbiome in COVID-19.Emerging microbes & infections · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Xiangning BaiDepartment of Laboratory Medicine, Division of Clinical Microbiology, ANA Futura, Karolinska Institute, 141 52 Stockholm, Sweden.
Aswathy NarayananDepartment of Medicine Huddinge, Division of Infectious Diseases, Karolinska Institute, 141 86 Stockholm, Sweden.
Magdalena SkagerbergDepartment of Infectious Diseases, Karolinska University Hospital, 141 86 Stockholm, Sweden.
Rafael Ceña-DiezDepartment of Medicine Huddinge, Division of Infectious Diseases, Karolinska Institute, 141 86 Stockholm, Sweden.ORCID 0000-0001-9987-395X
Christian G GiskeDepartment of Laboratory Medicine, Division of Clinical Microbiology, ANA Futura, Karolinska Institute, 141 52 Stockholm, Sweden.
Kristoffer StrålinDepartment of Medicine Huddinge, Division of Infectious Diseases, Karolinska Institute, 141 86 Stockholm, Sweden.
Anders SönnerborgDepartment of Laboratory Medicine, Division of Clinical Microbiology, ANA Futura, Karolinska Institute, 141 52 Stockholm, Sweden.
Karolinska University Hospital · SEKarolinska Institutet · SEOslo University Hospital · NO

Funding

ALF Med 20 FoUI-953887Swedish Research Council 2020-02129, 2017-05848, 2016-01675
6 · The paper itself

Abstract

The upper respiratory tract (URT) microbiome can contribute to the acquisition and severity of respiratory viral infections. The described associations between URT microbiota and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are limited at microbiota genus level and by the lack of functional interpretation. Our study, therefore, characterized the URT bacterial microbiome at species level and their encoded pathways in patients with COVID-19 and correlated these to clinical outcomes. Whole metagenome sequencing was performed on nasopharyngeal samples from hospitalized patients with critical COVID-19 (

Indexed as

COVID-19inflammationmicrobiomerespiratory statusSARS-CoV-2upper respiratory tract

Identifiers

PMID35625719
PMCPMC9138573
OpenAlexW4224315595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.