ReviewBiomedicines2022
Neuroinflammation in Post-Traumatic Stress Disorder.
Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 78 citations in OpenAlex.
- Dynamic immune and metabolic dysregulation in women with post-traumatic stress disorder: Longitudinal transcriptomic insights following sexual assault.Molecular psychiatry · 2026Article
- Oxidative stress and impaired cardiovagal baroreflex sensitivity in young adults with post-traumatic stress disorder.Experimental physiology · 2026Article
- Traditional Fermented Multi-Grain Supernatant (Ogi-baba Omidun) Restores Hypothalamic-Pituitary-Testicular Axis Function in a Juvenile Double-Hit PTSD-Neuroinflammation Rat Model.Molecular neurobiology · 2026Article
- From Stress to Neurodegeneration: A New Look at the Pathogenesis of Parkinson's Disease.Biomedicines · 2026Review
- The NLRP3 Inflammasome in Neuropsychiatric Disorders: Molecular Mechanisms and Emerging Therapeutic Strategies.International journal of molecular sciences · 2026Review
- Neuroprotective Role of Morin Hydrate in Stress-Re-stress (SRS) Rat Model of PTSD: Mitigation of Cognitive Dysfunction, Anxiety, and Depression via Regulation of Oxidative Stress and Neuroinflammation.Neurochemical research · 2026Article
- Article
- PTSD and Audio Vestibular Symptoms: A Two-Way Street Driven by the Amygdala? A Speculative Hypothesis.Brain sciences · 2026Review
- Resistance exercise alleviates overactive bladder by attenuating detrusor oxidative stress via peroxynitrite reduction.European journal of medical research · 2026Article
- Low dose naltrexone for fibromyalgia: case series demonstrating pain relief and other health benefits.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Ketogenic metabolic therapy for treatment-resistant post-traumatic stress disorder (PTSD): a retrospective case report.Frontiers in nutrition · 2026Article
- The gut microbiota-immune-brain axis in post-traumatic stress disorder: mechanistic integration and translational prospects.Frontiers in immunology · 2026Review
- Causal relationship between inflammatory cytokines and posttraumatic stress disorder: a Mendelian randomization study and potential mechanism analysis.European journal of psychotraumatology · 2025Article
- Correction of Vitamin D Deficiency Improves PTSD Symptoms in Gulf War Veterans.Brain sciences · 2025Article
- Comprehensive Explorations and Preliminary Experimental Verification of RNA Modification-Related Diagnostic Markers in the Subtype Classification of Peripheral Blood-Derived Mononuclear Cells Derived from Post-Traumatic Stress Disorder Patients.Diseases (Basel, Switzerland) · 2025Article
- The role of small extracellular vesicles in post-traumatic stress disorder.Global medical genetics · 2025Review
- Review
- The Effects of General Mental Health Symptomatology, COVID Anxiety, and Sociodemographic Factors on Pandemic-Induced Negative and Positive Trauma Effects: A Polish Survey from the Late Stages of the Pandemic.Journal of clinical medicine · 2025Article
- Modulation of adult hippocampal neurogenesis by interleukin 1 signaling.Neurobiology of sleep and circadian rhythms · 2025Article
- Association between post-traumatic stress disorder levels and serum inflammatory factors in patients undergoing digit replantation.Frontiers in neuroscience · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Post-traumatic stress disorder (PTSD) is a well-known mental illness, which is caused by various stressors, including memories of past physical assaults and psychological pressure. It is diagnosed as a mental and behavioral disorder, but increasing evidence is linking it to the immune system and inflammatory response. Studies on the relationship between inflammation and PTSD revealed that patients with PTSD had increased levels of inflammatory cytokine biomarkers, such as interleukin-1, interleukin-6, tumor necrosis factor-α, nuclear factor-κB, and C-reactive protein, compared with healthy controls. In addition, animal model experiments imitating PTSD patients suggested the role of inflammation in the pathogenesis and pathophysiology of PTSD. In this review, we summarize the definition of PTSD and its association with increased inflammation, its mechanisms, and future predictable diseases and treatment possibilities. We also discuss anti-inflammatory treatments to address inflammation in PTSD.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.