Evidence map›Paper›PMID 35625597›Full record

ArticleBiomolecules2022

Intracellular and Extracellular Antifreeze Protein Significantly Improves Mammalian Cell Cryopreservation.

Jonathan A Sreter, Thomas L Foxall, Krisztina Varga

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Cryopreservation of jaguar (Animal reproduction · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Extended Temperature Range of the Ice-Binding Protein Activity.Langmuir : the ACS journal of surfaces and colloids · 2024
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jonathan A SreterDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH 03824, USA.ORCID 0000-0001-9562-741X
Thomas L FoxallDepartment of Biological Sciences, University of New Hampshire, Durham, NH 03824, USA.
Krisztina VargaDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH 03824, USA.ORCID 0000-0003-2810-0997
University of New Hampshire · US

Funding

TLR-TRIF mediated induction of GLI3 modulates innate inflammatory responsesP20GM113131 · NIGMS · UNIVERSITY OF NEW HAMPSHIRE · PI Sean Stoddart Coleman Edington · 2017 to 2026
$22.8M
The Structure-Activity Relationship of a Macrocycle with Antifreeze PropertiesR15GM135903 · NIGMS · KEENE STATE COLLEGE · PI BAURES, PAUL W. · 2020 to 2020
$376k
NIGMS NIH HHS P20 GM113131NIGMS NIH HHS R15 GM135903NIH HHS GM135903NIH HHS P20GM113131
6 · The paper itself

Abstract

Cell cryopreservation is an essential part of the biotechnology, food, and health care industries. There is a need to develop more effective, less toxic cryoprotective agents (CPAs) and methods, especially for mammalian cells. We investigated the impact of an insect antifreeze protein from

Indexed as

Cryoprotective AgentsDimethyl Sulfoxidealpha-FetoproteinsAnimalsAntifreeze ProteinsCryopreservationCulture MediaHumansMammalsalpha-FetoproteinsAntifreeze ProteinsCryoprotective AgentsCulture MediaDimethyl Sulfoxideantifreeze proteincryopreservationcryoprotectantsfreezingmammalian cells

Identifiers

PMID35625597
PMCPMC9139014
OpenAlexW4280564099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.