ArticleBiomolecules2022
Osteoblast Attachment on Titanium Coated with Hydroxyapatite by Atomic Layer Deposition.
Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Development of alendronate-loaded 3D-printed PCL/LDH scaffolds for controlled drug delivery in bone tissue engineering.RSC advances · 2026Article
- Functionalizing biomaterials for osseointegration - microRNAs at the crossroads of bone formation and immune modulation.Bone & joint research · 2026Article
- Foot and ankle biomaterials: a comprehensive review of current applications, challenges, and future directions.Journal of orthopaedic translation · 2026Review
- Ultrathin ALD Coatings of Zr and V Oxides on Anodic TiOACS applied materials & interfaces · 2025Article
- The Deposition of Hydroxyapatite Particles Within an Organic Matrix on the Surface of Poly(lactic acid).International journal of molecular sciences · 2024Article
- Ultrathin TiOACS applied materials & interfaces · 2024Article
- Osteoblast Attachment on Bioactive Glass Air Particle Abrasion-Induced Calcium Phosphate Coating.Bioengineering (Basel, Switzerland) · 2024Article
- Enhancement of biocompatibility of anodic nanotube structures on biomedical Ti-6Al-4V alloy via ultrathin TiOFrontiers in bioengineering and biotechnology · 2024Article
- In Vitro Study of Zirconia Surface Modification for Dental Implants by Atomic Layer Deposition.International journal of molecular sciences · 2023Article
- Monocyte Differentiation on Atomic Layer-Deposited (ALD) Hydroxyapatite Coating on Titanium Substrate.Molecules (Basel, Switzerland) · 2023Article
- Construction of functional surfaces for dental implants to enhance osseointegration.Frontiers in bioengineering and biotechnology · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe increasing demand for bone implants with improved osseointegration properties has prompted researchers to develop various coating types for metal implants. Atomic layer deposition (ALD) is a method for producing nanoscale coatings conformally on complex three-dimensional surfaces. We have prepared hydroxyapatite (HA) coating on titanium (Ti) substrate with the ALD method and analyzed the biocompatibility of this coating in terms of cell adhesion and viability.
methodsHA coatings were prepared on Ti substrates by depositing CaCO
resultsVinculin staining revealed similar focal adhesion-like structures on ALD-HA as on glass slides and bone, albeit on ALD-HA and bone the structures were thinner compared to glass slides. This might be due to thin and broad focal adhesions on complex three-dimensional surfaces of ALD-HA and bone. The MTT test showed comparable cell viability on ALD-HA, glass slides and bone.
conclusionALD-HA coating was shown to be biocompatible in regard to cell adhesion and viability. This leads to new opportunities in developing improved implant coatings for better osseointegration and implant survival.
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