Evidence map›Paper›PMID 35625397›Full record

ArticleBiology2022

IL-10 Producing Regulatory B Cells Mediated Protection against Murine Malaria Pathogenesis.

Meenu Kalkal, Rubika Chauhan, Reva Sharan Thakur, Mrinalini Tiwari, Veena Pande, Jyoti Das

Open access · goldAbstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Early enhanced control ofInfection and immunity · 2026
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  4. The LEF1-LAG3 axis regulates CD4Parasites & vectors · 2026
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  5. Early enhanced control ofbioRxiv : the preprint server for biology · 2026
    Article
  6. Review
  7. Review
  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Meenu KalkalParasite-Host Biology, ICMR-National Institute of Malaria Research, Dwarka, New Delhi 110077, India.ORCID 0000-0003-2300-6408
Rubika ChauhanParasite-Host Biology, ICMR-National Institute of Malaria Research, Dwarka, New Delhi 110077, India.
Reva Sharan ThakurParasite-Host Biology, ICMR-National Institute of Malaria Research, Dwarka, New Delhi 110077, India.
Mrinalini TiwariParasite-Host Biology, ICMR-National Institute of Malaria Research, Dwarka, New Delhi 110077, India.
Veena PandeBiotechnology Department, Kumaun University, Nainital 263001, India.
Jyoti DasParasite-Host Biology, ICMR-National Institute of Malaria Research, Dwarka, New Delhi 110077, India.ORCID 0000-0001-8877-1069
National Institute of Malaria Research · INKumaun University · IN

Funding

National Institute of Malaria Research Intramural
6 · The paper itself

Abstract

Various immune cells are known to participate in combating infection. Regulatory B cells represent a subset of B cells that take part in immunomodulation and control inflammation. The immunoregulatory function of regulatory B cells has been shown in various murine models of several disorders. In this study, a comparable IL-10 competent B-10 cell subset (regulatory B cells) was characterized during lethal and non-lethal infection with malaria parasites using the mouse model. We observed that infection of Balb/c mice with

Indexed as

B-cellsimmunomodulationinterleukin-10 (IL-10)malariaPlasmodiumregulatory B cells (Bregs)

Identifiers

PMID35625397
PMCPMC9138363
OpenAlexW4282930543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.