Evidence map›Paper›PMID 35625332›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Phenotypic Adaptation to Antiseptics and Effects on Biofilm Formation Capacity and Antibiotic Resistance in Clinical Isolates of Early Colonizers in Dental Plaque.

David L Auer, Xiaojun Mao, Annette Carola Anderson, Denise Muehler, Annette Wittmer, Christiane von Ohle, Diana Wolff, Cornelia Frese, Karl-Anton Hiller, Tim Maisch and 4 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Impact of Sublethal Disinfectant Exposure on Antibiotic Resistance Patterns of Pseudomonasaeruginosa.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2025
    Article
  5. Article
  6. Article
  7. Observational
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

David L AuerDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, 93053 Regensburg, Germany.
Xiaojun MaoDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, 93053 Regensburg, Germany.
Annette Carola AndersonDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine, Faculty of Medicine, University of Freiburg, 79085 Freiburg im Breisgau, Germany.ORCID 0000-0002-4489-1939
Denise MuehlerDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, 93053 Regensburg, Germany.ORCID 0000-0002-3799-5123
Annette WittmerInstitute of Medical Microbiology and Hygiene, Faculty of Medicine, University of Freiburg, 79085 Freiburg im Breisgau, Germany.
Christiane von OhleDepartment of Conservative Dentistry, Periodontology and Endodontology, University Hospital Tübingen, 72076 Tübingen, Germany.
Diana WolffDepartment of Conservative Dentistry, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Cornelia FreseDepartment of Conservative Dentistry, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Karl-Anton HillerDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, 93053 Regensburg, Germany.ORCID 0000-0002-4726-9555
Tim MaischDepartment of Dermatology, University Hospital Regensburg, 93053 Regensburg, Germany.
Wolfgang BuchallaDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, 93053 Regensburg, Germany.
Elmar HellwigDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine, Faculty of Medicine, University of Freiburg, 79085 Freiburg im Breisgau, Germany.
Ali Al-AhmadDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine, Faculty of Medicine, University of Freiburg, 79085 Freiburg im Breisgau, Germany.ORCID 0000-0001-8769-599X
Fabian CieplikDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, 93053 Regensburg, Germany.ORCID 0000-0002-1750-7380
University Hospital Regensburg · DEUniversity of Freiburg · DEHeidelberg University · DE

Funding

Deutsche Forschungsgemeinschaft AL 1179/4-1Deutsche Forschungsgemeinschaft CI 263/3-1
6 · The paper itself

Abstract

Despite the wide-spread use of antiseptics in dental practice and oral care products, there is little public awareness of potential risks associated with antiseptic resistance and potentially concomitant cross-resistance. Therefore, the aim of this study was to investigate potential phenotypic adaptation in 177 clinical isolates of early colonizers of dental plaque (

Indexed as

adaptationantibioticantisepticbiocidecetylpyridinium chloridechlorhexidineoral biofilmresistance

Identifiers

PMID35625332
PMCPMC9137571
OpenAlexW4280518041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.