Evidence map›Paper›PMID 35625326›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Exploration of Trends in Antimicrobial Use and Their Determinants Based on Dispensing Information Collected from Pharmacies throughout Japan: A First Report.

Yuichi Muraki, Masayuki Maeda, Ryo Inose, Koki Yoshimura, Naoki Onizuka, Masao Takahashi, Eiji Kawakami, Yoshiaki Shikamura, Naotaka Son, Makoto Iwashita and 8 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Yuichi MurakiDepartment of Clinical Pharmacoepidemiology, Kyoto Pharmaceutical University, Kyoto 607-8414, Japan.ORCID 0000-0001-6951-5676
Masayuki MaedaDivision of Infection Control Sciences, Department of Clinical Pharmacy, School of Pharmacy, Showa University, Tokyo 142-8555, Japan.ORCID 0000-0002-5917-668X
Ryo InoseDepartment of Clinical Pharmacoepidemiology, Kyoto Pharmaceutical University, Kyoto 607-8414, Japan.ORCID 0000-0003-4874-0377
Koki YoshimuraDepartment of Clinical Pharmacoepidemiology, Kyoto Pharmaceutical University, Kyoto 607-8414, Japan.
Naoki OnizukaDepartment of Clinical Pharmacoepidemiology, Kyoto Pharmaceutical University, Kyoto 607-8414, Japan.
Masao TakahashiTakahashi Pharmacy, Tokyo 135-0005, Japan.
Eiji KawakamiKawakami Dispensing Pharmacy, Kyoto 617-0814, Japan.
Yoshiaki ShikamuraFaculty of Pharmaceutical Sciences, Tokyo University of Science, Tokyo 133-0033, Japan.ORCID 0000-0003-1070-803X
Naotaka SonPharmacy Co., Ltd., Tokyo 153-0062, Japan.
Makoto IwashitaTotosato Pharmacy, Nagano 384-1103, Japan.
Manabu SuzukiGifu Pharmaceutical Association, Gifu 500-8146, Japan.
Masayuki YokoiPascal Pharmacy, Ogaki 525-0031, Japan.
Hirokazu HorikoshiMarusho Pharmacy, Osaka 543-0023, Japan.
Yasuaki AokiJapan Pharmaceutical Association, Tokyo 160-8389, Japan.
Michiyo KawanaJapan Pharmaceutical Association, Tokyo 160-8389, Japan.
Miwako KameiJapan Pharmaceutical Association, Tokyo 160-8389, Japan.
Hajime HashibaJapan Pharmaceutical Association, Tokyo 160-8389, Japan.
Choichiro MiyazakiJapan Pharmaceutical Association, Tokyo 160-8389, Japan.

Funding

Japan Pharmaceutical Association None
6 · The paper itself

Abstract

The purpose of this study was to evaluate the defined daily doses (DDD)/1000 prescriptions/month (DPM) as a new indicator that can be used in pharmacies, and to describe antimicrobial use patterns in pharmacies nationwide in Japan. Dispensing volumes, number of prescriptions received, and facility information were obtained from 2638 pharmacies that participated in a survey. DPM was calculated based on the dispensing volume and number of prescriptions, which are routinely collected data that are simple to use. Use of third-generation cephalosporins, quinolones, and macrolides in pharmacies that received prescriptions primarily from hospitals or clinics decreased from January 2019 to January 2021. In particular, the antimicrobial use was higher in otorhinolaryngology departments than in other departments, despite a decrease in the antimicrobial use. In the linear multiple regression analysis, otorhinolaryngology department was independently associated with the third-generation cephalosporin, quinolone, and macrolide prescription in all periods. This study reveals for the first-time trends in antimicrobial use through a new indicator using the volume of drugs dispensed in pharmacies throughout Japan. Antimicrobial use differed by the medical department, suggesting the need to target interventions according to the department type.

Indexed as

antimicrobial resistanceantimicrobial usedefined daily dosesurveillance

Identifiers

PMID35625326
PMCPMC9138112

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.