Evidence map›Paper›PMID 35625317›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Synergism between the Synthetic Antibacterial and Antibiofilm Peptide (SAAP)-148 and Halicin.

Miriam E van Gent, Tanny J K van der Reijden, Patrick R Lennard, Adriëtte W de Visser, Bep Schonkeren-Ravensbergen, Natasja Dolezal, Robert A Cordfunke, Jan Wouter Drijfhout, Peter H Nibbering

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. In Vivo Effect of Halicin on Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Miriam E van GentDepartment of Infectious Diseases, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0002-9751-0650
Tanny J K van der ReijdenDepartment of Infectious Diseases, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Patrick R LennardDepartment of Infectious Diseases, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0002-8390-0463
Adriëtte W de VisserDepartment of Infectious Diseases, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Bep Schonkeren-RavensbergenDepartment of Infectious Diseases, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Natasja DolezalDepartment of Immunology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Robert A CordfunkeDepartment of Immunology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0002-7200-7434
Jan Wouter DrijfhoutDepartment of Immunology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Peter H NibberingDepartment of Infectious Diseases, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Leiden University Medical Center · NL

Funding

Dutch Research Council 16434
6 · The paper itself

Abstract

Recently, using a deep learning approach, the novel antibiotic halicin was discovered. We compared the antibacterial activities of two novel bactericidal antimicrobial agents, i.e., the synthetic antibacterial and antibiofilm peptide (SAAP)-148 with this antibiotic halicin. Results revealed that SAAP-148 was more effective than halicin in killing planktonic bacteria of antimicrobial-resistant (AMR)

Indexed as

antimicrobial resistancebiofilmbladder infectionhalicinSAAP-148skin wound infectionsynergy

Identifiers

PMID35625317
PMCPMC9137631
OpenAlexW4280516795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.