Evidence map›Paper›PMID 35625286›Full record

ArticleAntibiotics (Basel, Switzerland)2022

The Impact of a Post-Prescription Review and Feedback Antimicrobial Stewardship Program in Lebanon.

Anita Shallal, Chloe Lahoud, Dunia Merhej, Sandra Youssef, Jelena Verkler, Linda Kaljee, Tyler Prentiss, Seema Joshi, Marcus Zervos, Madonna Matar

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Anita ShallalDivision of Infectious Diseases, Henry Ford Hospital, Detroit, MI 48202, USA.ORCID 0000-0002-1940-3622
Chloe LahoudDivision of Infectious Diseases, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0003-2346-8733
Dunia MerhejNotre Dame des Secours University Hospital, Byblos 1401, Lebanon.
Sandra YoussefNotre Dame des Secours University Hospital, Byblos 1401, Lebanon.
Jelena VerklerDivision of Infectious Diseases, Henry Ford Hospital, Detroit, MI 48202, USA.
Linda KaljeeGlobal Health Initiative, Henry Ford Hospital, Detroit, MI 48202, USA.
Tyler PrentissGlobal Health Initiative, Henry Ford Hospital, Detroit, MI 48202, USA.
Seema JoshiDivision of Infectious Diseases, Henry Ford Hospital, Detroit, MI 48202, USA.
Marcus ZervosDivision of Infectious Diseases, Henry Ford Hospital, Detroit, MI 48202, USA.
Madonna MatarNotre Dame des Secours University Hospital, Byblos 1401, Lebanon.ORCID 0000-0003-4870-8879
Henry Ford Hospital · USCentre Hospitalier Universitaire Notre Dame des Secours · LBBrigham and Women's Hospital · USHoly Spirit University of Kaslik · LBWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial stewardship programs (ASPs) are effective means to optimize prescribing practices. They are under-utilized in the Middle East where many challenges exist for ASP implementation. We assessed the effectiveness of infectious disease physician-driven post-prescription review and feedback as an ASP in Lebanon. This prospective cohort study was conducted over an 18-month period in the medical, surgical, and intensive care units of a tertiary care hospital. It consisted of three phases: the baseline, intervention, and follow-up. There was a washout period of two months between each phase. Patients aged ≥16 years receiving 48 h of antibiotics were included. During the intervention phase, the AMS team reviewed antimicrobial use within 72 h post-prescription and gave alternate recommendations based on the guidelines for use. The acceptance of the recommendations was measured at 72 h. The primary outcome of the study was days of therapy per 1000 study patient days. A total of 328 patients were recruited in the baseline phase (August−October 2020), 467 patients in the intervention phase (January−June 2021), and 301 patients in the post-intervention phase (September−December 2021). The total days of therapy decreased from 11.46 during the baseline phase to 8.64 during the intervention phase (p < 0.001). Intervention acceptance occurred 88.5% of the time. The infectious disease physician-driven implementation of an ASP was successful in reducing antibiotic utilization in an acute care setting in Lebanon.

Indexed as

antimicrobial stewardshipCOVID-19disaster planningglobal health

Identifiers

PMID35625286
PMCPMC9138162
OpenAlexW4280538906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.