Evidence map›Paper›PMID 35625252›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Clindamycin Efficacy for

Audrey Courdurié, Romain Lotte, Raymond Ruimy, Vincent Cauhape, Michel Carles, Marc-Olivier Gauci, Pascal Boileau, Johan Courjon

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Successful Treatment ofOpen forum infectious diseases · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Audrey CourduriéInfectious Diseases Department, Université Côte d'Azur, CHU Nice, 06202 Nice, France.
Romain LotteDepartment of Bacteriology, Université Côte d'Azur, CHU Nice, 06202 Nice, France.
Raymond RuimyDepartment of Bacteriology, Université Côte d'Azur, CHU Nice, 06202 Nice, France.
Vincent CauhapeInfectious Diseases Department, Université Côte d'Azur, CHU Nice, 06202 Nice, France.
Michel CarlesInfectious Diseases Department, Université Côte d'Azur, CHU Nice, 06202 Nice, France.
Marc-Olivier GauciInstitut Universitaire Locomoteur & Sport (IULS), Unité de Recherche Clinique Côte d'Azur (UR2CA), Hôpital Pasteur 2 CHU de Nice, Université Côte D'Azur, 06000 Nice, France.ORCID 0000-0003-2228-7084
Pascal BoileauICR-Institut de Chirurgie Réparatrice Locomoteur et Sports-Groupe KANTYS, 06000 Nice, France.
Johan CourjonInfectious Diseases Department, Université Côte d'Azur, CHU Nice, 06202 Nice, France.
Inserm · FRUniversité Côte d'Azur · FRCentre Hospitalier Universitaire de Nice · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clindamycin is an antibiotic with high bioavailability and appropriate bone diffusion, often proposed as an alternative in guidelines for

methodsA retrospective analysis was conducted at the University Hospital of Nice (France) between 2010 and 2019. We included patients with one shoulder implant surgical procedure and at least one

resultsForty-eight SIJI were identified and 33 were treated with clindamycin, among which 25 were treated with monotherapy. The median duration of clindamycin antibiotherapy was 6 weeks. The average follow-up was 45 months; one patient was lost to follow-up. Twenty-seven patients out of 33 (82%) were cured with clindamycin, compared to 9/12 (75%) with other antibiotics. The rate of favorable outcomes increased to 27/31 (87%) with clindamycin and to 9/10 (90%) for other antibiotics when no septic revision strategies were excluded (

conclusionsThe therapeutic strategy based on one- or two-stage revision associated with 6 weeks of clindamycin seems to be effective.

Indexed as

clindamycinCutibacterium acnesshoulder implant

Identifiers

PMID35625252
PMCPMC9137462
OpenAlexW4225125975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.