Evidence map›Paper›PMID 35625239›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Diversity of Monofloral Honey Based on the Antimicrobial and Antioxidant Potential.

Anca Hulea, Diana Obiștioiu, Ileana Cocan, Ersilia Alexa, Monica Negrea, Alina-Georgeta Neacșu, Călin Hulea, Corina Pascu, Luminita Costinar, Ionica Iancu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Pharmaco-Toxicological Effects ofAntioxidants (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Honey as a Natural Antimicrobial.Antibiotics (Basel, Switzerland) · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Antioxidants (Basel, Switzerland) · 2023
    Article
  15. Enhancing the Antimicrobial Effect of Ozone withMolecules (Basel, Switzerland) · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Anca HuleaFaculty of Veterinary Medicine, Banat University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" Timisoara, Calea Aradului No. 119, 300645 Timisoara, Romania.
Diana ObiștioiuFaculty of Veterinary Medicine, Banat University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" Timisoara, Calea Aradului No. 119, 300645 Timisoara, Romania.ORCID 0000-0002-1481-6954
Ileana CocanFaculty of Food Engineering, Banat University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" Timisoara, Calea Aradului No. 119, 300645 Timisoara, Romania.ORCID 0000-0001-7621-402X
Ersilia AlexaFaculty of Food Engineering, Banat University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" Timisoara, Calea Aradului No. 119, 300645 Timisoara, Romania.ORCID 0000-0003-4641-7365
Monica NegreaFaculty of Food Engineering, Banat University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" Timisoara, Calea Aradului No. 119, 300645 Timisoara, Romania.ORCID 0000-0001-9765-8498
Alina-Georgeta NeacșuFaculty of Agriculture, Banat University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" Timisoara, Calea Aradului No. 119, 300641 Timisoara, Romania.ORCID 0000-0003-3998-3537
Călin HuleaFaculty of Veterinary Medicine, Banat University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" Timisoara, Calea Aradului No. 119, 300645 Timisoara, Romania.
Corina PascuFaculty of Veterinary Medicine, Banat University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" Timisoara, Calea Aradului No. 119, 300645 Timisoara, Romania.ORCID 0000-0002-1013-0437
Luminita CostinarFaculty of Veterinary Medicine, Banat University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" Timisoara, Calea Aradului No. 119, 300645 Timisoara, Romania.
Ionica IancuFaculty of Veterinary Medicine, Banat University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" Timisoara, Calea Aradului No. 119, 300645 Timisoara, Romania.
Emil TîrziuFaculty of Veterinary Medicine, Banat University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" Timisoara, Calea Aradului No. 119, 300645 Timisoara, Romania.
Viorel HermanFaculty of Veterinary Medicine, Banat University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" Timisoara, Calea Aradului No. 119, 300645 Timisoara, Romania.ORCID 0000-0001-7118-6488
Univesity of Life Science "King Mihai I" from Timisoara · RO

Funding

Banat University of Agricultural Sciences and Veterinary Medicine Increasing the impact of excellence research on the capacity for innovation and technology transfer within USAMVB Timișoara" code 6PFE, submitted in the competition Program 1 - Development of the national system of research - development, Subprogram 1.2 -
6 · The paper itself

Abstract

This study aimed to investigate the antioxidant profile and the antimicrobial activity of four different types of monofloral honey (manuka (MH), brassica rapeseed (BH), acacia (AH), and linden honey (LH)) against some bacterial/fungal ATCC strains and some multidrug-resistant strains isolated from chronic otitis in dogs. For the characterisation of the antioxidant profile of each honey, we extracted the honey samples by hydroalcoholic extraction and analysed them in terms of total polyphenols (TPC), total flavonoids (TFC), and 2,2-diphenyl-1-picrylhydrazyl (DPPH) using the spectrophotometric method. The antimicrobial activity was determined using the microdilution method at concentrations of 10%, 15%, and 20%, with the results expressed in OD (optical density) calculated as BIR% (bacterial inhibition rate)/MIR% (mycelial inhibition rate). The antioxidant characterisation of the analysed honey samples showed the highest antioxidant activity and concentrations of TPC and TFC in MH, followed by LH. MH was proven to be the most effective on most clinical isolates concerning the antimicrobial activity in comparison with BH, AH, and LH. Except for B. cepacia and P. vulgaris, all the clinical isolates were sensitive to the antibacterial activity of honey. Regarding the ATCC strains, MH 10% was the most effective in inhibiting all the strains tested except for P. aeruginosa. In conclusion, the efficacy classification in our study was MH > BH > AH > LH.

Indexed as

acacia honeyantimicrobial activityantioxidantsbrassica rapeseed honeyhoneylinden honeymanuka honey

Identifiers

PMID35625239
PMCPMC9137981
OpenAlexW4280600398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.