Evidence map›Paper›PMID 35625238›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Whole-Genome Sequencing of a Colistin-Resistant

Noel-David Nogbou, Mbudzeni Ramashia, Granny Marumo Nkawane, Mushal Allam, Chikwelu Lawrence Obi, Andrew Munyalo Musyoki

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Comparative analysis ofFrontiers in microbiology · 2025
    Article
  3. TracingMicroorganisms · 2024
    Article
  4. Genomic insights into the adaptation of Acinetobacter johnsonii RB2-047 to the heavy metal-contaminated subsurface mine environment.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  5. Colistin Resistance inAntibiotics (Basel, Switzerland) · 2023
    Review
  6. Detection of antibiotic-resistant canine originFrontiers in veterinary science · 2023
    Article
  7. Comparative genomics and molecular epidemiology of colistin-resistantComputational and structural biotechnology journal · 2023
    Article
  8. Article
  9. Molecular characterisation ofFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Noel-David NogbouMicrobiological Pathology Department, School of Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.ORCID 0000-0003-0938-0073
Mbudzeni RamashiaMicrobiological Pathology Department, School of Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.ORCID 0000-0003-0593-5190
Granny Marumo NkawaneMicrobiological Pathology Department, School of Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.ORCID 0000-0003-2658-9792
Mushal AllamDepartment of Genetics and Genomics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab Emirates.ORCID 0000-0002-9875-6716
Chikwelu Lawrence ObiSchool of Sciences and Technology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.
Andrew Munyalo MusyokiMicrobiological Pathology Department, School of Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.
Sefako Makgatho Health Sciences University · ZAUnited Arab Emirates University · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsAn antimicrobial susceptibility test, conventional PCR, quantitative real-time PCR, phenotypic evaluation of the efflux pump, and whole-genome sequencing and analysis were performed on the isolate.

resultsThe antimicrobial susceptibility pattern revealed a resistance to piperacillin/tazobactam, ceftazidime, cefepime, cefotaxime/ceftriaxone, imipenem, meropenem, gentamycin, ciprofloxacin, trimethoprim/sulfamethoxazole, tigecycline, and colistin. A broth microdilution test confirmed the colistin resistance. Conventional PCR and quantitative real-time PCR investigations revealed the presence of

conclusionsThe mosaic of the virulence factors coupled with the resistance-associated genes and the phenotypic resistance profile highlights the risk that this strain is at this South African tertiary health facility.

Indexed as

Acinetobacter baumanniicolistin resistanceresistance mechanismSouth Africavirulence factors

Identifiers

PMID35625238
PMCPMC9138137
OpenAlexW4282927719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.