ArticleAnimals : an open access journal from MDPI2022
Risk Factors for Exercise-Associated Sudden Cardiac Death in Thoroughbred Racehorses.
Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 18 citations in OpenAlex.
- Case report: exercise-associated sudden death in a Thoroughbred racehorse with cardiac lesions.Veterinary research communications · 2026Article
- Pathology of sudden death in racehorses: a review.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2026Article
- Delta (Δ) 12-lead electrocardiography and vectorcardiography to identify the origin of focally induced atrial and ventricular premature depolarizations in horses.Journal of veterinary internal medicine · 2026Article
- Cardiac arrhythmia prevalence and risk factors in 24-h electrocardiograms of sedentary horses.Equine veterinary journal · 2026Article
- Cardiac arrhythmias during intense exercise in Thoroughbred racehorses: frequency and association with subsequent race performance.Journal of veterinary internal medicine · 2026Article
- Selected Large-Animal Models of Ventricular Arrhythmias.Biology · 2026Review
- Novel risk factors associated with fatal musculoskeletal injury in Thoroughbreds in North American racing (2009-2023).Equine veterinary journal · 2026Article
- Association of heart rate variability, exercise intensity and exercising arrhythmias with competition results in eventing horses.Equine veterinary journal · 2025Article
- Performance horses as a model for exercise-associated cardiac arrhythmias and sudden cardiac death.Journal of molecular and cellular cardiology plus · 2025Review
- Heritability of sudden cardiac death in Thoroughbred racehorses.Equine veterinary journal · 2025Article
- Arrhythmias across the tree of life: comparative insights for human electrophysiology.Frontiers in cardiovascular medicine · 2025Review
- Linkage of jockey falls and injuries with racehorse injuries and fatalities in Thoroughbred flat racing in Victoria, Australia.Frontiers in veterinary science · 2024Article
- Anomalous Incidence of Fatal Musculoskeletal Injury in North American 2-Year-Old Thoroughbred Racehorses in the Year 2020.Animals : an open access journal from MDPI · 2023Article
- The Reporting of Racehorse Fatalities in New Zealand Thoroughbred Flat Racing in the 2011/12-2021/22 Seasons.Animals : an open access journal from MDPI · 2023Article
- QT Interval and Cardiac Restitution Ratio Complexity in Standardbred Racehorses From Rest to Maximal Effort: Insights Into Arrhythmia Risk.Journal of veterinary internal medicineArticle
- Associations between postrace atrial fibrillation and measures of performance, racing history and airway disease in horses.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Cardiac arrhythmias resulting in sudden cardiac death (SCD) are an important cause of racehorse fatalities. The objective of this study was to determine risk factors for SCD in Thoroughbreds by evaluating a sample with a policy of mandatory post-mortem following racing or training fatalities. Risk factors were compared between case horses with SCD (n = 57) and control horses with other fatal injury (OFI, n = 188) by univariable and multivariable logistic regression. Survival in years for horses with SCD was compared to OFI using the Kaplan−Meier method with log rank test. The following variables were most important in the multiple logistic model: Horses with SCD were more likely to die during training than during racing, SCD (42/57, 74%) vs. OFI (82/188, 44%; odds ratio [OR], 95% confidence interval [CI], 2.5, 1.2−5.4; p = 0.01), had fewer lifetime starts, median (interquartile range [IQR]), SCD (3.0 [0.0−9.0]) vs. OFI (9.0 [0.0−22.8]; OR, 95% CI, 0.96, 0.9−1.0; p = 0.02 and were less likely to be entire (uncastrated) males, SCD 9/57 (16%) vs. OFI (46/188, 25%; OR, 95% CI, 0.47, 0.1−0.9; p = 0.03). Survival in years (median (IQR)) for horses with SCD was 3.6 (3.1−4.4), which was shorter than OFI (4.5 [3.1−6.0], hazard ratio, 95%CI, 1.6,1.2−2.3; p < 0.001). SCD occurs more commonly in training than racing, which suggests exercise intensity is less important in precipitating this fatality. In this study, SCD occurred early in the careers of affected horses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.