Evidence map›Paper›PMID 35625120›Full record

ArticleAnimals : an open access journal from MDPI2022

Genome-Wide Identification and Characterization of Long Non-Coding RNAs in Embryo Muscle of Chicken.

Lingbin Liu, Lingtong Ren, Anfang Liu, Jinxin Wang, Jianhua Wang, Qigui Wang

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Lingbin LiuKey Laboratory of Biorheological Science and Technology, Chongqing University, Ministry of Education, Chongqing 400045, China.ORCID 0000-0001-9266-9868
Lingtong RenCollege of Animal Science and Technology, Southwest University, Beibei, Chongqing 400715, China.
Anfang LiuCollege of Animal Science and Technology, Southwest University, Beibei, Chongqing 400715, China.
Jinxin WangDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0001-6482-2917
Jianhua WangKey Laboratory of Biorheological Science and Technology, Chongqing University, Ministry of Education, Chongqing 400045, China.
Qigui WangChongQing Academy of Animal Sciences, Rongchang, Chongqing 402460, China.
Chongqing University · CNSouthwest University · CNChongqing Academy of Animal Science · CN

Funding

China Postdoctoral Science Foundation 2020M673157Municipal Special Financial Fund for Chongqing Academy of Animal Science 21501National Natural Science Foundation of China 32002155Special Key Project of Chongqing Technology Innovation and Application Development cstc2019jscx-gksbX0107Visiting Scholar Foundation of Key Laboratory of Biorheological Science and Technology (Chongqing University) CQKLBST-2020-006
6 · The paper itself

Abstract

Embryonic muscle development determines the state of muscle development and muscle morphological structure size. Recent studies have found that long non-coding RNAs (lncRNAs) could influence numerous cellular processes and regulated growth and development of flora and fauna. A total of 1056 differentially expressed lncRNAs were identified by comparing the different time points during embryonic muscle development, which included 874 new lncRNAs. Here, we found that there were different gene expression patterns on the 12th day of embryo development (E12). Herein, WGCNA and correlation analyses were used to predict lncRNA function on E12 through the screening and identification of lncRNAs related to muscle development in the embryo leg muscles of Chengkou mountain chickens at different times. GO and KEGG functional enrichment analysis was performed on target genes involved in cis-regulation and trans-regulation. An interaction network diagram was constructed based on the muscle development pathways, such as Wnt, FoxO, and PI3K-AKT signaling pathways, to determine the interaction between mRNAs and lncRNAs. This study preliminarily determined the lncRNA expression pattern of muscle development during the middle and late embryonic stages of Chengkou mountain chickens, and provided a basis to analyze the molecular mechanism of muscle development.

Indexed as

chickenembryo muscle developmentlncRNAsregulatory network constructionWGCNA

Identifiers

PMID35625120
PMCPMC9137640
OpenAlexW4280651585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.