Evidence map›Paper›PMID 35624994›Full record

ReviewBrain sciences2022

Olfactory Evaluation in Alzheimer's Disease Model Mice.

Jingjing Zhang, Zixuan Zhao, Siqi Sun, Jing Li, Yu Wang, Jingyin Dong, Su Yang, Yiyi Lou, Jing Yang, Weiyun Li and 1 more

Abstract readReview
In one paragraph

Review in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Diffusion MRI reveals amyloid plaque-associated cellular signatures through spatial transcriptomic integration.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Article
  4. Thermal Cycling Stimulation via Nasal Inhalation Attenuates AβInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Serial reversal learning in an olfactory discrimination task in 3xTg-AD mice.Learning & memory (Cold Spring Harbor, N.Y.) · 2023
    Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jingjing ZhangDepartment of Basic Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.
Zixuan ZhaoDepartment of Basic Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.
Siqi SunDepartment of Basic Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.
Jing LiInstitute of Neuroscience and Anatomy, School of Medicine, Zhejiang University, Hangzhou 310058, China.
Yu WangHangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou 310053, China.
Jingyin DongDepartment of Basic Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.
Su YangSir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310020, China.
Yiyi LouSir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310020, China.
Jing YangDepartment of Basic Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.
Weiyun LiDepartment of Basic Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.
Shanshan LiDepartment of Basic Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.

Funding

Hangzhou Agriculture and Social development research project 20201203B149National Natural Science Foundation of China 81901154Zhejiang Basic Public Welfare Research Program LGD21H250001Zhejiang Basic Public Welfare Research Program LGD22H250001
6 · The paper itself

Abstract

Olfactory dysfunction is considered a pre-cognitive biomarker of Alzheimer's disease (AD). Because the olfactory system is highly conserved across species, mouse models corresponding to various AD etiologies have been bred and used in numerous studies on olfactory disorders. The olfactory behavior test is a method required for early olfactory dysfunction detection in AD model mice. Here, we review the olfactory evaluation of AD model mice, focusing on traditional olfactory detection methods, olfactory behavior involving the olfactory cortex, and the results of olfactory behavior in AD model mice, aiming to provide some inspiration for further development of olfactory detection methods in AD model mice.

Indexed as

Alzheimer’s disease model miceolfactory behavior testolfactory evaluation

Identifiers

PMID35624994
PMCPMC9139301

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.