Evidence map›Paper›PMID 35624901›Full record

ArticleBrain sciences2022

Neuropsychiatric Disorders in Pediatric Long COVID-19: A Case Series.

Rosa Savino, Anna N Polito, Giulia Arcidiacono, Mariacristina Poliseno, Sergio Lo Caputo

Open access · goldAbstract readCase Reports
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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  16. Psychiatric and neurological complications of long COVID.Journal of psychiatric research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rosa SavinoDepartment of Woman and Child, Neuropsychiatry for Child and Adolescent Unit, General Hospital "Riuniti" of Foggia, 71122 Foggia, Italy.ORCID 0000-0001-6439-0317
Anna N PolitoDepartment of Woman and Child, Neuropsychiatry for Child and Adolescent Unit, General Hospital "Riuniti" of Foggia, 71122 Foggia, Italy.
Giulia ArcidiaconoDepartment of Woman and Child, Neuropsychiatry for Child and Adolescent Unit, General Hospital "Riuniti" of Foggia, 71122 Foggia, Italy.
Mariacristina PolisenoDepartment of Clinical and Experimental Medicine, Infectious Diseases Unit, General Hospital "Riuniti" of Foggia, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-9896-489X
Sergio Lo CaputoDepartment of Clinical and Experimental Medicine, Infectious Diseases Unit, General Hospital "Riuniti" of Foggia, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-4729-7548
Ospedali Riuniti di Foggia · ITUniversity of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few data are available regarding the incidence and the evolution of neuropsychiatric manifestations in children with a history of COVID-19. We herein report five consequent cases of pediatric patients with psychiatric and neurological symptoms of long COVID-19. All patients, mainly males, reported asymptomatic-to-mild COVID-19 and underwent home self-isolation. Abnormal movements, anxiety, and emotional dysregulation were the most recurrent symptoms observed from a few weeks to months after the resolution of the acute infection. A later onset was observed in younger patients. Blood tests and brain imaging resulted in negative results in all subjects; pharmacological and cognitive behavioral therapy was set. A multifactorial etiology could be hypothesized in these cases, as a result of a complex interplay between systemic and brain inflammation and environmental stress in vulnerable individuals. Longer follow-up is required to observe the evolution of neuropsychiatric manifestation in the present cohort and other young patients with previous SARS-CoV-2 infection.

Indexed as

COVID-19 haulerskynurenineslong COVID-19movement disordersneuroinflammationneuropsychiatric disorderspandemic stresspsychosisSARS-CoV-2 infection

Identifiers

PMID35624901
PMCPMC9138973
OpenAlexW4224225013

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.