Evidence map›Paper›PMID 35624767›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Valorization and Potential Antimicrobial Use of Olive Mill Wastewater (OMW) from Italian Olive Oil Production.

Eleonora Russo, Andrea Spallarossa, Antonio Comite, Marcello Pagliero, Patrizia Guida, Vittorio Belotti, Debora Caviglia, Anna Maria Schito

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Multifunctional NADES-Based Extracts fromMolecules (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Article
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  9. NaDES-Based Extracts by Microwave Activation fromMolecules (Basel, Switzerland) · 2025
    Article
  10. Olive mill wastewater: From by-product to smart antioxidant material.International journal of pharmaceutics: X · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Eleonora RussoDepartment of Pharmacy, University of Genova, Viale Benedetto XV, 3, 16132 Genoa, Italy.
Andrea SpallarossaDepartment of Pharmacy, University of Genova, Viale Benedetto XV, 3, 16132 Genoa, Italy.ORCID 0000-0002-3360-7146
Antonio ComiteDepartment of Chemistry and Industrial Chemistry, University of Genova, Via Dodecaneso, 31, 16146 Genoa, Italy.ORCID 0000-0003-0321-5915
Marcello PaglieroDepartment of Chemistry and Industrial Chemistry, University of Genova, Via Dodecaneso, 31, 16146 Genoa, Italy.ORCID 0000-0002-2119-9528
Patrizia GuidaDepartment of Phisics, University of Genova, Via Dodecaneso, 31, 16146 Genoa, Italy.
Vittorio BelottiDepartment of Mechanical, Energy, Management and Transport Engineering, University of Genova, Via alla Opera Pia, 15, 16100 Genoa, Italy.
Debora CavigliaDepartment of Integrated Surgical and Diagnostic Sciences, University of Genova, Viale Benedetto XV, 6, 16132 Genoa, Italy.
Anna Maria SchitoDepartment of Integrated Surgical and Diagnostic Sciences, University of Genova, Viale Benedetto XV, 6, 16132 Genoa, Italy.
University of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The production of olive oil generates olive mill wastewater (OMW) which essentially derives from the processing, treatment and pressing of olives in mills. Traditional milling processes require a quantity of water varying between 40 and 120 L per quintal of pressed olives, generating a considerable amount of wastewater. It is thus necessary to reduce process water and enhance its use to implement the concept of a circular economy. To this end, our preliminary work was dedicated to water purification by means of suitable and efficient filtration systems. The microfiltered OMW was firstly concentrated through reverse osmosis. Then, an additional concentration step was carried out via vacuum membrane distillation using hydrophobic hollow fiber membranes. The application of the membrane-based processes allowed the recovery of a purified water and the concentration of valuable polyphenols in a smaller volume. The different fractions obtained from the purification have been tested for the determination of the antioxidant power (DPPH assay) and dosage of polyphenols (Folin-Ciocalteu assay) and were characterized using IR spectroscopy. All samples showed relevant antioxidant activity (percentage range: 10-80%) and total phenolic content in the 1.5-15 g GAE/L range. The obtained fractions were tested for their antimicrobial effect on numerous clinical isolates of Gram-positive and Gram-negative species, resistant and multi-resistant to current antibiotic drugs. OMW samples showed widespread activity against the considered (phyto)pathogens (MIC range 8-16 mg/mL) thus supporting the value of this waste material in the (phyto)pharmaceutical field.

Indexed as

antibacterial activityantioxidant activitycircular economymembrane processesolive mill wastewaterpolyphenols

Identifiers

PMID35624767
PMCPMC9137489
OpenAlexW4225376168

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.