Evidence map›Paper›PMID 35624698›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Comment on Yeste et al. Polyphenols and IUGR Pregnancies: Intrauterine Growth Restriction and Hydroxytyrosol Affect the Development and Neurotransmitter Profile of the Hippocampus in a Pig Model.

Glòria Garrabou, Ana Sandra Hernández, Mariona Guitart-Mampel, Elena Escalada-Casellas, Gemma Malats-Revelles, Sara Castro-Barquero, Ana María Ruiz-León, Kilian Vellvé, Rosa Casas, Francesc Cardellach and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Glòria GarrabouMuscle Research and Mitochondrial Function Laboratory, Cellex-IDIBAPS, Faculty of Medicine and Health Sciences, University of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0001-8973-9933
Ana Sandra HernándezBiomedical Network Research Centre on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Mariona Guitart-MampelMuscle Research and Mitochondrial Function Laboratory, Cellex-IDIBAPS, Faculty of Medicine and Health Sciences, University of Barcelona, 08036 Barcelona, Spain.
Elena Escalada-CasellasMuscle Research and Mitochondrial Function Laboratory, Cellex-IDIBAPS, Faculty of Medicine and Health Sciences, University of Barcelona, 08036 Barcelona, Spain.
Gemma Malats-RevellesMuscle Research and Mitochondrial Function Laboratory, Cellex-IDIBAPS, Faculty of Medicine and Health Sciences, University of Barcelona, 08036 Barcelona, Spain.
Sara Castro-BarqueroInternal Medicine Unit, Medicine Department, Hospital Clínic of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0002-6876-5443
Ana María Ruiz-LeónInternal Medicine Unit, Medicine Department, Hospital Clínic of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0001-8180-5991
Kilian VellvéBiomedical Network Research Centre on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Rosa CasasInternal Medicine Unit, Medicine Department, Hospital Clínic of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0002-0211-9166
Francesc CardellachMuscle Research and Mitochondrial Function Laboratory, Cellex-IDIBAPS, Faculty of Medicine and Health Sciences, University of Barcelona, 08036 Barcelona, Spain.
Fàtima CrispiBiomedical Network Research Centre on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Francesc Josep García-GarcíaMuscle Research and Mitochondrial Function Laboratory, Cellex-IDIBAPS, Faculty of Medicine and Health Sciences, University of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0001-9021-0324
Instituto de Salud Carlos III · ESHospital Sant Joan de Déu Barcelona · ES

Funding

Instituto de Salud Carlos III PI1800451Instituto de Salud Carlos III PI1800498Instituto de Salud Carlos III PI2100935
6 · The paper itself

Abstract

Intrauterine growth restriction (IUGR) affects 5-10% of newborns and increases the risks of intrauterine demise, neonatal morbidity, and death. In their recent publication, Yeste et al. found the benefits of hydroxytyrosol supplementation on brain remodeling from an IUGR pig model. Additionally, we found a significant decrease in phenolic alcohol (tyrosol and hydroxytyrosol) intake in IUGR pregnant women. Altogether, these findings support the notion that dietetic interventions, through supplementation but mostly via a balanced diet, can ameliorate IUGR complications. Furthermore, diet intervention combined with early biomarkers may allow clinicians to eventually anticipate IUGR diagnosis and help avoid one of the most frequent causes of newborn mortality and morbidity.

Indexed as

balanced diethydroxytyrosolintrauterine growth restrictionMediterranean dietsupplementationtyrosol

Identifiers

PMID35624698
PMCPMC9137715
OpenAlexW4282925486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.