ArticleAntioxidants (Basel, Switzerland)2022
Drinking Water Supplemented with Acidifiers Improves the Growth Performance of Weaned Pigs and Potentially Regulates Antioxidant Capacity, Immunity, and Gastrointestinal Microbiota Diversity.
Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 35 citations in OpenAlex.
- Combined Supplementation of Live Yeast and Yeast Postbiotics Enhances Antioxidant Capacity and Intestinal Health in Weaned Piglets.Antioxidants (Basel, Switzerland) · 2026Article
- Isolation and characterization of a novel strain of Rhizopus arrhizus for effective biodegradation and detoxification of zearalenone.World journal of microbiology & biotechnology · 2026Article
- Effect of fermented grape pomace on growth performance and intestinal health of weaned piglets.Animal microbiome · 2026Article
- Piceatannol enhances antioxidant capacity and growth in weaned piglets by regulating of Nrf2-mediated redox homeostasis and modulating of the related gut microbiota.Journal of animal science and biotechnology · 2026Article
- Redox Homeostasis in Poultry/Animal Production.Antioxidants (Basel, Switzerland) · 2025Article
- The role of human-pig interactions in modulating gut microbiota, stress, and performance.Porcine health management · 2025Article
- Effects of Lactic Acid and Glyceryl Lactate on Growth Performance, Antioxidant Capacity, and Intestinal Health of Piglets.Antioxidants (Basel, Switzerland) · 2025Article
- Effects of organic acid-preserved cereal grains in sow diets during late gestation and lactation on the performance and faecal microbiota of sows and their offspring.Journal of animal science and biotechnology · 2025Article
- The Role of Nutrition Across Production Stages to Improve Sow Longevity.Animals : an open access journal from MDPI · 2025Review
- Relationship between water hardness, pH, and organic acid requirement for effective water acidification in swine operations.Translational animal science · 2025Article
- Alternatives to antibiotics for sustainable livestock production in the context of the One Health approach: tackling a common foe.Frontiers in veterinary science · 2025Review
- Effects of dietary acidifiers and other low acid-binding capacity formulation strategies on weanling pig growth performance and fecal dry matter.Translational animal science · 2025Article
- A Commercial Clay-Based Material as a Carrier for Targeted Lysozyme Delivery in Animal Feed.Nanomaterials (Basel, Switzerland) · 2023Article
- Plant essential oils improve growth performance by increasing antioxidative capacity, enhancing intestinal barrier function, and modulating gut microbiota in Muscovy ducks.Poultry science · 2023Article
- Stevioside Improves Antioxidant Capacity and Intestinal Barrier Function while Attenuating Inflammation and Apoptosis by Regulating the NF-κB/MAPK Pathways in Diquat-Induced Oxidative Stress of IPEC-J2 Cells.Antioxidants (Basel, Switzerland) · 2023Article
- Effects of Dietary Probiotics and Acidifiers on the Production Performance, Colostrum Components, Serum Antioxidant Activity and Hormone Levels, and Gene Expression in Mammary Tissue of Lactating Sows.Animals : an open access journal from MDPI · 2023Article
- Early supplementation with zinc proteinate does not change rectal microbiota but increases growth performance by improving antioxidant capacity and plasma zinc concentration in preweaned dairy calves.Frontiers in veterinary science · 2023Article
- Acidifiers Attenuate Diquat-Induced Oxidative Stress and Inflammatory Responses by Regulating NF-κB/MAPK/COX-2 Pathways in IPEC-J2 Cells.Antioxidants (Basel, Switzerland) · 2022Article
- Antioxidants in Animal Feed.Antioxidants (Basel, Switzerland) · 2022Article
- Insights in the Development and Uses of Alternatives to Antibiotic Growth Promoters in Poultry and Swine Production.Antibiotics (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
This study evaluated the potential effects of adding acidifiers to the drinking water on the growth performance, complete blood count, antioxidant indicators, and diversity of gastrointestinal microbiota for weaned pigs. A total of 400 weaned pigs were randomly divided into four treatments. Pigs were fed the same basal diet and given either water (no acidifier was added, control) or water plus blends of different formulas of acidifiers (acidifier A1, A2, or A3) for 35 days. On d 18 and 35 of the experimental period, 64 pigs (four pigs per pen) were randomly selected to collect blood for a CBC test (n = 128) and an antioxidant indicators test (n = 128); 24 pigs (six pigs per group) were randomly selected to collect fresh feces (n = 48) from the rectum for 16S rRNA gene sequencing. Compared to the control, supplementing the drinking water with acidifiers improved the growth performance and survival rate of weaned pigs. Acidifier groups also increased serum catalase (CAT) and total antioxidant capacity (T-AOC) activities, while also displaying a decreased malondialdehyde (MDA) concentration compared to the control. The relative abundance of Firmicutes in the acidifier A1 group was greater than that in the control group (p < 0.05) on d 35; the relative abundance of Lactobacillus in the acidifier A1 group was greater than that in the control group (p < 0.05) on d 18 and 35. The microbial species Subdoligranulum or Ruminococcaceae_UCG-005 had significantly positive correlations with ADG and ADFI or with serum antioxidant indicators, respectively. These findings suggest that supplementing the drinking water with an acidifier has a potential as an antioxidant, which was reflected in the improvement of growth performance, immunity, antioxidant capacity, and intestinal flora.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.