Evidence map›Paper›PMID 35624659›Full record

ArticleBiosensors2022

Energy-Efficient, On-Demand Activation of Biosensor Arrays for Long-Term Continuous Health Monitoring.

Jonathan Lundquist, Benjamin Horstmann, Dmitry Pestov, Umit Ozgur, Vitaliy Avrutin, Erdem Topsakal

Abstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jonathan LundquistDepartment of Electrical and Computer Engineering, College of Engineering, Virginia Commonwealth University, 907 Floyd Ave, Richmond, VA 23284, USA.ORCID 0000-0002-2351-0535
Benjamin HorstmannDepartment of Electrical and Computer Engineering, College of Engineering, Virginia Commonwealth University, 907 Floyd Ave, Richmond, VA 23284, USA.
Dmitry PestovNanomaterials Core Characterization Facility, College of Engineering, Virginia Commonwealth University, 907 Floyd Ave, Richmond, VA 23284, USA.
Umit OzgurDepartment of Electrical and Computer Engineering, College of Engineering, Virginia Commonwealth University, 907 Floyd Ave, Richmond, VA 23284, USA.
Vitaliy AvrutinDepartment of Electrical and Computer Engineering, College of Engineering, Virginia Commonwealth University, 907 Floyd Ave, Richmond, VA 23284, USA.
Erdem TopsakalDepartment of Electrical and Computer Engineering, College of Engineering, Virginia Commonwealth University, 907 Floyd Ave, Richmond, VA 23284, USA.

Funding

C. Kenneth and Dianne Wright Center for Clinical and Translational Research (CCTR) Endow-ment Fund of the Virginia Commonwelth University 2-92880
6 · The paper itself

Abstract

Wearable biosensors for continuous health monitoring, particularly those used for glucose detection, have a limited operational lifetime due to biodegradation and fouling. As a result, patients must change sensors frequently, increasing cost and patient discomfort. Arrays of multiple sensors, where the individual devices can be activated on demand, increase overall operational longevity, thereby reducing cost and improving patient outcomes. This work demonstrates the feasibility of this approach via decomposition of combustible nitrocellulose membranes that protect the individual sensors from exposure to bioanalytes using a current pulse. Metal contacts, connected by graphene-loaded PEDOT:PSS polymer on the surface of the membrane, deliver the required energy to decompose the membrane. Nitrocellulose membranes with a thickness of less than 1 µm consistently transfer on to polydimethylsiloxane (PDMS) wells. An electrical energy as low as 68 mJ has been shown to suffice for membrane decomposition.

Indexed as

Biosensing TechniquesGraphiteCollodionHumansPolymersCollodionGraphitePolymersbiosensor arraycontinuous glucose monitoringpulse current activation

Identifiers

PMID35624659
PMCPMC9138492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.