ArticleBiosensors2022
Chiral Liquid Crystal Microdroplets for Sensing Phospholipid Amphiphiles.
Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Article
- Molecular Orientation Behavior of Lyotropic Liquid Crystal-Carbon Dot Hybrids in Microfluidic Confinement.International journal of molecular sciences · 2024Article
- Tuning Molecular Orientation Responses of Microfluidic Liquid Crystal Dispersions to Colloid and Polymer Flows.International journal of molecular sciences · 2023Article
- Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Designing simple, sensitive, fast, and inexpensive readout devices to detect biological molecules and biomarkers is crucial for early diagnosis and treatments. Here, we have studied the interaction of the chiral liquid crystal (CLC) and biomolecules at the liquid crystal (LC)-droplet interface. CLC droplets with high and low chirality were prepared using a microfluidic device. We explored the reconfiguration of the CLC molecules confined in droplets in the presence of 1,2-diauroyl-sn-glycero3-phosphatidylcholine (DLPC) phospholipid. Cross-polarized optical microscopy and spectrometry techniques were employed to monitor the effect of droplet size and DLPC concentration on the structural reorganization of the CLC molecules. Our results showed that in the presence of DLPC, the chiral LC droplets transition from planar to homeotropic ordering through a multistage molecular reorientation. However, this reconfiguration process in the low-chirality droplets happened three times faster than in high-chirality ones. Applying spectrometry and image analysis, we found that the change in the chiral droplets' Bragg reflection can be correlated with the CLC-DLPC interactions.
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Registered trials
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