Evidence map›Paper›PMID 35624588›Full record

ArticleBiosensors2022

An Interfacial Affinity Interaction-Based Method for Detecting HOTAIR lncRNA in Cancer Plasma Samples.

Kimberley Clack, Narshone Soda, Surasak Kasetsirikul, Richard Kline, Carlos Salomon, Muhammad J A Shiddiky

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Kimberley ClackSchool of Environment and Science, Nathan Campus, Griffith University, Nathan, QLD 4111, Australia.
Narshone SodaQueensland Micro and Nanotechnology Centre, Nathan Campus, Griffith University, Nathan, QLD 4111, Australia.ORCID 0000-0002-1921-7176
Surasak KasetsirikulQueensland Micro and Nanotechnology Centre, Nathan Campus, Griffith University, Nathan, QLD 4111, Australia.ORCID 0000-0001-9767-1254
Richard KlineSection of Gynaecologic Oncology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA.
Carlos SalomonSection of Gynaecologic Oncology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA.ORCID 0000-0003-4474-0046
Muhammad J A ShiddikySchool of Environment and Science, Nathan Campus, Griffith University, Nathan, QLD 4111, Australia.ORCID 0000-0003-4526-4109
Griffith University · AUOchsner Medical Center · USUniversidad de Santiago de Chile · CL

Funding

National Health and Medical Research Council APP1199984
6 · The paper itself

Abstract

Long non-coding RNA Homeobox transcript antisense intergenic RNA (HOTAIR) is recognized as a participant in different processes of normal cell development. Aberrant overexpression of HOTAIR contributes to the initiation, growth, and invasiveness of ovarian cancer. Using the affinity interaction of target HOTAIR lncRNA sequences towards a screen-printed gold electrode (SPE-Au), herein we report on a novel, rapid and simple method to detect HOTAIR sequences. HOTAIR lncRNA sequences were first extracted from ovarian cancer cell lines and patient plasma samples and were magnetically captured and purified by complimentary capture probe-functionalized magnetic beads. Isolated target HOTAIR lncRNAs were directly adsorbed onto unmodified screen-printed gold electrodes (SPE-Au) for direct quantification with [Fe(CN)

Indexed as

MicroRNAsOvarian NeoplasmsRNA, Long NoncodingApoptosisCell Line, TumorFemaleGenes, HomeoboxGoldHumansRNA, AntisenseGoldMicroRNAsRNA, AntisenseRNA, Long Noncodingaffinity interactionelectrochemical detectionHOTAIR lncRNAinterfacial biosensingovarian cancerRNA biosensor

Identifiers

PMID35624588
PMCPMC9139111
OpenAlexW4225152019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.