ReviewBiosensors2022
Properties and Applications of Graphene and Its Derivatives in Biosensors for Cancer Detection: A Comprehensive Review.
Review in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 96 citations in OpenAlex.
- Biosensors for oral cancer detection: a scoping review.Diagnostic pathology · 2026Article
- Review
- Graphene-Based Chemical Field-Effect Transistors: Impact of Electric Double Layer Model and Quantum Capacitance on NaMicromachines · 2026Article
- Electrochemical Detection of Cancer Biomarkers: From Molecular Sensing to Clinical Translation.Biosensors · 2026Review
- Numerical Simulation of InP and MXene-Based SPR Sensor for Different Cancerous Cells Detection.Cell biochemistry and biophysics · 2025Article
- A comprehensive review of graphene-based biosensors: Fabrication, applications, characterization and future perspectives-A review.APL bioengineering · 2025Review
- Nanomaterial-enhanced biosensors for polycystic ovarian syndrome diagnosis and pathophysiological insights.Mikrochimica acta · 2025Review
- Graphene Nanocomposites in the Targeting Tumor Microenvironment: Recent Advances in TME Reprogramming.International journal of molecular sciences · 2025Review
- Unraveling Charge Transfer Mechanisms in Graphene-Quantum Dot Hybrids for High-Sensitivity Biosensing.Biosensors · 2025Article
- Graphene and Its Derivatives for Electrochemical Sensing.Sensors (Basel, Switzerland) · 2025Review
- Optical Based Surface Plasmon Resonance Sensor for the Detection of the Various Kind of Cancerous Cell.Cell biochemistry and biophysics · 2025Article
- Nanomaterials for liver cancer targeting: research progress and future prospects.Frontiers in immunology · 2025Review
- Biomedical applications of graphene-based nanomaterials: recent progress, challenges, and prospects in highly sensitive biosensors.Discover nano · 2024Review
- Nucleic acid and nanomaterial-assisted signal-amplified strategies in fluorescent analysis of circulating tumor cells and small extracellular vesicles.Analytical and bioanalytical chemistry · 2023Review
- Article
- Application of Various Optical and Electrochemical Nanobiosensors for Detecting Cancer Antigen 125 (CA-125): A Review.Biosensors · 2023Review
- Two-Dimensional Graphitic Carbon Nitride (g-CJournal of functional biomaterials · 2022Review
- Vertical Graphene-Based Biosensor for Tumor Cell Dielectric Signature Evaluation.Micromachines · 2022Article
- Highly Sensitive TiOBiosensors · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer is one of the deadliest diseases worldwide, and there is a critical need for diagnostic platforms for applications in early cancer detection. The diagnosis of cancer can be made by identifying abnormal cell characteristics such as functional changes, a number of vital proteins in the body, abnormal genetic mutations and structural changes, and so on. Identifying biomarker candidates such as DNA, RNA, mRNA, aptamers, metabolomic biomolecules, enzymes, and proteins is one of the most important challenges. In order to eliminate such challenges, emerging biomarkers can be identified by designing a suitable biosensor. One of the most powerful technologies in development is biosensor technology based on nanostructures. Recently, graphene and its derivatives have been used for diverse diagnostic and therapeutic approaches. Graphene-based biosensors have exhibited significant performance with excellent sensitivity, selectivity, stability, and a wide detection range. In this review, the principle of technology, advances, and challenges in graphene-based biosensors such as field-effect transistors (FET), fluorescence sensors, SPR biosensors, and electrochemical biosensors to detect different cancer cells is systematically discussed. Additionally, we provide an outlook on the properties, applications, and challenges of graphene and its derivatives, such as Graphene Oxide (GO), Reduced Graphene Oxide (RGO), and Graphene Quantum Dots (GQDs), in early cancer detection by nanobiosensors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.