Evidence map›Paper›PMID 35624468›Full record

ArticleWorld journal of emergency surgery : WJES2022

In-hospital mortality associated with necrotizing soft tissue infection due to Vibrio vulnificus: a matched-pair cohort study.

Chih-Yao Chang, Kai-Hsiang Wu, Po-Han Wu, Shang-Kai Hung, Cheng-Ting Hsiao, Shu-Ruei Wu, Chia-Peng Chang

Open access · goldAbstract read
In one paragraph

Article in World journal of emergency surgery : WJES, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. [Clinical application of multidisciplinary team in the diagnosis and treatment of chronic refractory wounds].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
    Article
  3. Article
  4. Machine Learning Approach to ClassifyInfection and drug resistance · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chih-Yao ChangDepartment of Emergency Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Kai-Hsiang WuDepartment of Emergency Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Po-Han WuDepartment of Emergency Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Shang-Kai HungDepartment of Emergency Medicine, Chang Gung Memorial Hospital, Taoyüan, Taiwan.
Cheng-Ting HsiaoDepartment of Emergency Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Shu-Ruei WuDepartment of Pediatric, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Chia-Peng ChangDepartment of Emergency Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan. giovanni850730@gmail.com.
Chiayi Chang Gung Memorial Hospital · TWChang Gung Memorial Hospital · TWKaohsiung Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt remains unclear whether Vibrio vulnificus necrotizing soft tissue infection (NSTI) is associated with higher mortality compared with non-Vibrio NSTI. This study's objective was to compare outcomes including in-hospital mortality and prognosis between patients with V. vulnificus NSTI and those with non-Vibrio NSTI.

methodA retrospective 1:2 matched-pair cohort study of hospitalized patients with NSTI diagnosed by surgical finding was conducted in two tertiary hospitals in southern Taiwan between January 2015 and January 2020. In-hospital outcomes (mortality, length of stay) were compared between patients with and without V. vulnificus infection. We performed multiple imputation using chained equations followed by multivariable regression analyses fitted with generalized estimating equations to account for clustering within matched pairs. All-cause in-hospital mortality and length of stay during hospitalization were compared for NSTI patients with and without V. vulnificus.

resultA total of 135 patients were included, 45 in V. vulnificus NSTI group and 90 in non-Vibrio group. The V. vulnificus NSTI patients had higher mortality and longer hospital stays. Multivariable logistic regression analysis revealed that V. vulnificus NSTI was significantly associated with higher in-hospital mortality compared with non-Vibrio NSTI (adjusted odds ratio = 1.52; 95% confidence interval 1.36-1.70; p < 0.01).

conclusionVibrio vulnificus NSTI was associated with higher in-hospital mortality and longer hospital stay which may increase health care costs, suggesting that preventing V. vulnificus infection is essential.

Indexed as

Fasciitis, NecrotizingSoft Tissue InfectionsVibrio vulnificusCohort StudiesHospital MortalityHumansRetrospective StudiesMortalityNecrotizing soft tissue infectionVibrio vulnificus

Identifiers

PMID35624468
PMCPMC9145496
OpenAlexW4281678120

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.